Atorvastatin intermediates

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135456 tn?1301441224 895-8. Atorvastatin does not exhibit antiviral activity against HCV at conventional doses: a pilot clinical trial. O'Leary JG, Chan JL, McMahon CM, Chung RT. Gastrointestinal Unit, Department of Medicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA. Cholesterol biosynthesis is an integral part of HCV RNA replication. Not only does HCV RNA replicate on lipid rafts, but it also requires cholesterol intermediates to replicate.