Performance was expressed as observed area under the ROC curve (ObAUROC) and AUROC adjusted
for DANA (AdjAUROC). Performance of
APRI and Fibrotest-Fibrosure was higher than other biomarkers. In all etiologies, AdjAUROC was higher than ObAUROC. APRI showed its best performance in HCV mono-infected cases, with an AdjAUROC of 0.77 and 0.83 for greater than or equal to F2 and F4, respectively. In HBV and NASH patients, its performance was poor (AdjAUROC 0.