Metronidazole ketocanozole, miconazole, fluconazole, itraconazole, and nitrofurantoin pyrazinamide should be
used with caution. Beta-lactum
antibiotics can cause leucopenia, while amino glycosides can increase susceptibility to renal failure. Vancomycin can cause increased toxicity in patients with liver failure. Antibiotics which can produce hepatitis or cholestasis should be avoided or used with caution. Tuberculosis was more common in alcoholic and Child class C cirrhosis (Table 1).