As the liver fails, it’s ability to metabolize and rid the body of toxins becomes compromised, and these begin to build up
in the bloodstream. This toxin buildup, particularly high
ammonia levels, affects the central nervous system and results in fatigue, short-term memory loss, day-night sleep reversal, mental slowness and slurred speech. Patients with increased levels of these toxins may exhibit restless movement and asterixis, a hand-flapping tremor.