Factors associated with liver-specific mortality included age (hazard ratio [HR], 1.04
per year), male gender (HR, 1.42), mean
alcohol consumption (HR, 1.01 per weekly unit of alcohol consumption), and advanced liver fibrosis—the risk of liver-related death associated with Ishak fibrosis score of 6 was very high (HR, 61.7, compared with a fibrosis score of 0), whereas the risk was somewhat lower with a fibrosis score of 5 (HR, 15.7).