x/full
very interesting study which confirms why simvastatin, lowering cholesterol drug and
actos (diabetes 2 drug), have anti hbv activity lowering hbvdna, cancer risk, all this without problems of resistance and acting on all hbv mutants
conclusions:
The discovery of the mechanisms by which HBV is controlled by the hepatic metabolic milieu may broaden our understanding of the unique regulation of HBV expression and may also explain the mechanisms by which HBV induces liver pathologies.