This study was supported by grants from the National Institutes of Health and National Cancer Institute. Additional support was provided by
Takeda Pharmaceuticals, North America. Dr. Sanyal reports relationships with several companies including Exalenz, Takeda, Norgine, Astellas, Amylin, Intercept, Gilead, Roche, Salix, Sanofi-Aventis, Otsuka, and Orphan Therapeutics. Several study coauthors also report drug company relationships. Dr. Harrison has disclosed no relevant financial relationships.