zofran and liver disease

Zofran (Ondansetron ) is the med of choice for cancer patients and people with advanced liver disease also. It is used to prevent both nausea and vomiting. So it won't harm your liver should that be an issue. Cheers!

Get Botox injections for killer migraines every 3 months (it REALLY does stop them). Tried Zofran sublingual and throw it up, injections of Phernergan, suppositories. Have no regular appetite. If I do feel hungry I'll eat then end up puking within a couple hours. GI Dr. can't come up w/anything. I feel like crap and keep losing weight. Lost 60 lbs since 2007 simply from vomiting. Anybody want to offer ideas/suggestions.

Take omeprazole (empty stomach in morning) and antacid gel and see if it helps. Liver and kidney dysfunction is another cause. Hence kidney and liver function tests should be done. Other causes are diabetes and hypothyroidism. Electrolyte imbalance too can cause nausea. IBS, gluten or lactose intolerance, parasites in gut too can be the cause. A stool test should be done for worms, giardiasis etc. Chronic hepatitis or chronic infection of the gall bladder are the other possibilities.

Rex I am sorry you are having a tough time. But no matter what happens...it is not the end of the world not even close. The normal dosage of zofran in the US is 2x 8mg per day. Or 16 mg per day. You are talking 12 mg per day. Maybe you need more? Ask you doctor. If the drug is not working for you it probably means that the treatment is not the cause of your nausea. Zofran is a powerful and effective drug.

Stage 4 liver disease. When a person has cirrhosis the architecture of the liver changes and can be seen in a sonogram as shrinkage of the size of the liver and nodular growths on the surface of the liver. I trust you are seeing a gastroenterologist who is experienced in successfully treating patients with the new triple therapies for hepatitis C? They will know that only a biopsy can determined the stage of your liver disease. Hope this helps.

Interesting take, although I've never heard that particular line of thought before. Perhaps that doctor's line of thinking is that "chemo" = "cancer prevention", so that for stage 3 and stage 4 (who are at increased risk for liver cancer) it's "chemo.

I've been on Seasonique for about 2 years now, and I've been fine up until this summer when I started having severe pressure in my upper abdomen right under my ribcage. At first, it didn't matter WHAT I ate. That was in July. I JUST got diagnosed with GERD a couple weeks ago after my second upper endoscopy. It's been a HECK of a year...well, my symptoms are AWFUL. Thanksgiving, I had plain stuffing, mashed potatoes, green bean casserole, and pumpkin pie.

I used Zofran and compazine in the past (not on tx) Zofran If it's okay for him to take had no sides and worked the best for me, i've heard others say the same thing.

I took Zofran but it was for an off label use not for nausea which is its general use. Although it does control nausea it can create it in a minor way so the best thing to do is eat food with it. And it can be a bit sedating. Long term for Zofran a liver function test is advised as was by my provider but that's true of many medications including what I am on now.

I am really trying to see if my sister's condition has anything to do with her being given this shot. Last time she was given it was April 2013, she is currently in the hospital fighting for her life!! So with all the warnings about if you have a liver disease you shouldn't be taking this shot and the doctors are advising her liver isn't functioning and for it to be as far gone as it is, if she had come to hospital a year ago they wouldn't have been able to do anything!!

However, it is plausible that the research involving fatigue from chronic liver disease and Hepatitis C can be extrapolated to treatment of fatigue following treatment with Interferon and fatigue with other diseases, especially fatigue with Autoimmune Diseases and Chronic Fatigue Syndrome. Inflammation affecting neurotransmission appears to be a major factor in fatigue associated with all of these diseases/conditions.

Autoimmune disorders Sometimes a body’s immune system may begin to attack the liver or bile ducts causing inflammation and scarring which leads to a progressive form of liver disease. Examples of liver diseases believed to be caused by the immune system are primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC) and autoimmune hepatitis.

If your report says that your bilirubin is high, then you probably have jaundice (jaundice is the accumulation of bilirubin under the skin) and some type of liver disease that needs further testing and diagnosis. My two cents. Take care and God bless.

I was going thru a bottle of vodka every 2 to 3 days. I started having discomfort in the liver area with nausea fatigue and dry mouth. Had an lft done all normal. Still felt sick and went to the hospital lft normal except elevated bilirubin ultrasound normal. Had another lft couple of weeks after bilrubin down to 1.3. And another normal ultrasound. I still deal with right quadrant pain fatigue and nausea.

Hi, my name is Patty and I am 29 years old. To say that liver disease runs in my family would be a huge understatement, for my grandmother, aunt, and my father have all died of cirrhosis of the liver. Neither of the 3 were alcoholics either. Since the age of 18, I have had routine checkups and blood work, keeping a close eye on my liver function and health. In January of 2010, I was diagnosed with gallbladder disease and had surgery to remove it.

Hi, my name is Patty and I am 29 years old. To say that liver disease runs in my family would be a huge understatement, for my grandmother, aunt, and my father have all died of cirrhosis of the liver. Neither of the 3 were alcoholics either. Since the age of 18, I have had routine checkups and blood work, keeping a close eye on my liver function and health. In January of 2010, I was diagnosed with gallbladder disease and had surgery to remove it.

My daughter has been diagnosed with liver disease. She had hep c but that is now under control. She has developed varies in the aesophagus and these are banded every three months. She now has frequent nose bleeds and would like to know the significance of this. She had a drug problem and she also continues to drink alcohol in large amounts. What is the likely outcome of this as she does not listen to what I have to say regarding not drinking.

God made the liver to be self replicating and self healing. You can lose half of it to disease and it will heal itself if you treat it right. Please "Google" liver and you will see how wonderful it is.

He should be restricting sodium, taking medications to prevent ascites, varices, and hepatic encephalopathy, monitoring for liver cancer, restricting red meat, eating a liver friendly diet, and not drinking or taking medications that harm the liver. Obviously it is his choice whether or not to drink and whether or not to take care of his liver.

Also only patients with cirrhosis of the liver are prone to liver cancer. Liver cancer is a very serious and many times deadly disease. It is one the worse cancers you can have if not caught early. An MRI with contrast is the best test for determining if a growth in the liver is benign or cancer. You should have a MRI perform assuming whoever is doing the testing is experienced in diagnosing liver cancer. Most radiologists are not experts in liver tumors so they can miss cancer.

if you are 57yo you better consider treatment seriously and do all tests, cirrhosis and liver cancer jump to very high percentage after 50yo

If so, are your AST and ALT levels elevated as well?? If your bile flow becomes obstructed, this will damage your liver and your ALT and AST levels will rise. Let us know how things are going.

He suggested to have another chimo embolisation and also take medicine to kill the tumor. He has seen the CT scan and confirmed that Tumor is still primary, they couldn't find any where else. We are very concerned that the first Chimo embolisation didn't help to decrease AFP and if we delay surgery, tumor may spread. What will be the benefit of another chimo. Please help.

hi sorry you and your mom are going throgh this. liver disease is a horrible disease. can't offer much help since this is a hepatitis C forum but can tell you that if your mom hasn't stopped drinking then nothing will help her. many of the symptoms from end stage can be treated to make the patient more comfortable. make sure your mom is seeing a hepatologist (liver specialist).

need help with my husband he has hep c the treatment did not work he has scerossis of the liver and was recently released from the hospital from pancreatitis he has been hallucinateing recently one night so sever he riped out ivs and fled from the hospital the dr said his amonia levels arnt up so not realated his urine is so brown the dr said not realated.

Zofran and liver disease

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