Ziprasidone qtc
Common Questions and Answers about Ziprasidone qtc
geodon
Hi all. I am currently taking ziprasidone along with lamictil and topamax and Lexapro as well as an occasional Ativan. I have been taking 80mg ziprasidone-geodon- twice a day for almost three years now. It has made me gain almost 200 pounds! I need to get off of it but Everytime I do I start the withdrawal. Has anybody else been on geodon this long and gained so much weight? I even exercise and can't get it off.
(have been on said meds for about 5 years). her 2 suggestions are abilify and ziprasidone--i know nothing about either of these meds and would greatly appreciate any info. and input you may have. (i have until friday to research these meds and want to be as informed as possible) thank you very much in advance for your time.
Hi. I'm bipolar with psychosis and am currently tapering off of ziprasidone 80mg twice daily. I totally dropped my second dose along with lamotrigine,and Lexapro. So right now I am currently taking ziprasidone 80 mg, chantix 1mg, topamax 50mg 3x day, and ropinirole for side effects 1 mg once a day. I can't believe I actually made it through the night last night.
She is currently taking Cymbalta, Lamotrigine, Seroquel and Ziprasidone. She has been depressed for a few years but it suddenly got worse since she started to take ziprasidone. She has been taking it for about 2 weeks now. She informed us that she is hearing voices telling her to harm herself. She has experimented in cutting in the past, but yesterday she did it to the extreme resulting in numerous cuts to her arm. Is taking these four medications together a detriment to her mind set?
They started her on propralin and did a holter. During the holter monitoring her Qtc varied from 410 to about 480. Qtc was 410 when her heart rate was at the lowest, about 80 bmp. We continued on propralin after we got home from NICU.
Today at 3 months of age we had an apointment at our hospital where they again took ECG that showed QTc being 450. I have the ECG infront of me that says bmp 140, QT/QTC 310/450.
1X DAY, 5) VALACYCLOVIR 500MG 2X DAY, 6) ZIPRASIDONE 80MG. 2X DAY, 7) BUSPIRONE 15MG. 2X DAY, 8) METOPROLOL 25MG. 2X DAY, 9) THEOPHYLLINE 300MG. 2X DAY, 10) METOCLOPRAMIDE 5MG. 4X DAY, 11) LEVETIRACETAM 1,000MG. 3X DAY, 12) DIVALPROEXE 1,000MG. 3X DAY, 13) VIMPAT 100MG. 2X DAY, 14) ZONISAMIDE 100MG. 3BEDTIME, 15) LANSOPRAZOLE 30MG. 2X DAY, 16) SUCRALFATE 1GM. 3X DAY, 17) COLESTIPOL 1GM. 3X DAY. I'VE TRIED VIAGRA BEFORE WITH NO RESULTS. I WAS ON WELLBUTRIN BEFORE ZIPRASIDONE.
My holter only shows pac 7 beats and other than that is fine. My qt avg was 383 and qtc avg was 398. My QT max was 467 and QTc max was 480 msec. My percentage of QTc greater than 450 ms was 0%. The other two ekg that I was done about 4 years ago show qt 372 qtc 421 and qt 360 qtc 428. My echo is fine.
If you measure your QTc during times with high heart rate without physical activity or anxiety, your QTc may prolong.
What's important is that your REAL QT time, not corrected after the QTc formula, isn't above 500msec, because then (and only then) your risk of TdP increases. 95% of us have QT time at heart rate 60 of 360-440 msec (460 for women). That doesn't mean that 2,5% of us have LQTS (2,5% is above 440 and 2,5% is below 360).
From what I can gather from what you posted, 3.8% of the time your daughter has a QTc greater than 450 ms and a maximum QTc of 669 ms. Based on this information, more tests might be needed. Holter monitors are not perfect and the 669 ms is very concerning BUT this could certainly be an artifact/error.
Rare genetic conditions, electrolyte imbalances, and medications can cause elongation of the QTc interval.
I just obtained his medical records today and im very confused. The first EKG showed a QTc of 485 (0 days old), the second (1 day old) showed a QTc of 449, and the third (2 days old) showed a QTc of 459. The notes say the first EKG shows a prolonged QT interval and the notes from the second day say, "EKG shows QTC still prolonged" and the third note says his EKG is normal???? Why is 459 normal when it is longer than 449 which was considered prolonged?
I recently had a ECG that showed that I have long QTc of around 440. I've had about 20 ECG's in the past that all came up normal and no where near 440 or even above 400. Multiple stress tests, holters, and echo's come back normal as well. No one in my family has any heart problems and or has fainted.
Any one have any possible reason as to why I could have developed Long QT? I should also add that I'm on 12.
Besides some pvs and pacs (which The Dr said were causing my symptoms) i noticed in The report, in The QT chart, a max qt 436, max qtc 476, with heart rate 62. The % of max. Above 450 Qtc was 11.4%.
When asking my gp about that he took a calculator and with The info in The chart calculated The qtc and said the report was wrong and The max qtc was 443 ( wich i have read is long -=<440 ms-)
My question is, if this is posible, The report calculating it wrong. And what about The % number?
The first EKG showed a QTc of 485 (0 days old), the second (1 day old) showed a QTc of 449, and the third (2 days old) showed a QTc of 459. The notes say the first EKG shows a prolonged QT interval and the notes from the second day say, "EKG shows QTC still prolonged" and the third note says his EKG is normal???? Why is 459 normal when it is longer than 449 which was considered prolonged? Is the range for a 1 day old baby different from that of a two day old?
Do you know how fast your heart rate was during the ECG? Heart rate can have a huge effect on your QTc especially if they are using the Bazett formula (the most used and least accurate formula to determine Qtc).
Ziprasidone (Geodon) is a medication that must be withdrawn from very slowly. I would urge you, STRONGLY, to seek the advice of a qualified physician to help with this procedure. If you are unable to afford a doctors visit, please consult your local pharmacist in helping with your daughters withdrawl. Pharmacists are DOCTORS OF PHARMACOLOGY and can tell you the correct way to proceed. Please do not attempt this on your own.
Wore a 30 day Holter earlier this year and it was found I have intermittent episodes of Mobitz type 1 heart block and episodes of sinus arrythmia with dizziness. Was told by me EP that this nothing to worry about but my QTC was 460; follow up appointments measured it at 470, and 487. Exercise stress test showed prolongation of the QTc interval which got above 500 and also sudden drop in BP during cool down period of test.
The doctors took an ECG which showed a prolonged QT interval. The QTC was 536 ms (supposed to be below 460) but the doctors said that its nothing to worry about an to continue with exercise. An echocardiogram showed trace mitral valve regurgitation but apparently thats also harmless.
However, now I still get a racing heart with any exertion (174 bmp walking up 3 flights of stairs, 120 bpm walking around the house). My resting heart rate is 65-69 bmp.
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