Zetia and plaque
Common Questions and Answers about Zetia and plaque
zetia
If it were me I would give pravastatin a chance, but if I had the same side effects and I could not live with them, I would try something like Zetia. You could also add a fenofibrate like Tricor to lower your TGLs as well, very safe and no side effects. This will help lower your overall number but will not impact your LDL which is you main issue. You really need to get that under 130 with no other risk factors.
However I have had a hard time controlling my LDL level. I reacted to Lipitor and have had some luck with zetia but now I am using red yeast rice which had kept my levels around 100 when I was clean in my diet, which is hard to do in Mx. I am 56 and in very good shape with a body fat of about 17%. I just had a lipid panel done and here are my numbers: HDL 113, LDL 131, Trg 36. My HDLs have always been very high, but never this high. I don't smoke, my BP runs 115/70 on average.
Ever since I started taking Zetia and Fenofibrate together as recommended by my DR, I have put on pounds, am more bloated around the belly,a nd have persistent chest pains. I noticed this has occurred ever since I have been on cholesterol lowering meds, but is more noticeable in the past year with the new combination of drugs. I mentioned this to my DR and he said I need the drugs because of my High Cholesterol. What do you think?
Statins work in the liver and every commercial I have seen advises not to take if you have liver problems. Zetia works in the intestines.
Was the Zetia working?
If my memory serves me correctly, MikeS is taking statins and he had a TP. He is far more knowledgeable on the subject than I am and hopefully he will see this post and give his input.
Zetia is part of a class of drugs called cholesterol absorption inhibitors.
AST on upper end of normal at 40. The doctor said to stop the Lipitor...but stay on the Zetia...... and retest in 1-1/2 weeks which he did this past Sept. 30th. His ALP came down to normal at 91, his ALT stayed the same at 79, his AST stayed relatively the same at 42, but his GGTP went quite high at 240. The doctor's office called and told him to come in next week.
I’m a active 68 yr. old women, that has tried 3 different statins. Everyone gave me muscle problems. Then my GP put me on Zetia. Said it would be different. After two months on it, it was worst than the statins. Woke up one morning, couldn’t close my hand. My fingers were so swollen and my both thumb joints would not bend. When I tried to bend them they clicked and was very painful.
I finally went to a specialist in Baltimore who read my history which showed all the meds I was taking and he noticed that I was taking Zetia and told me that he believed Zetia caused chronic coughing in some people; so he looked it up on his computer and sure enough, that was one of the warnings. I stopped the Zetia and the coughing disappeared completely within a couple of weeks. The point here is that medicines, while helping one problem, frequently can cause another.
I just got off of zetia and welchol. I could not take statins. I tried them all. Used to take Niaspan and fenofibrate but they took me off cause both cause problems in some and had not 'reduced the incidence of cardiac events'. I think they have concluded that neither do Zetia, except when used with a statin, so it is the statin doing the work. I also think Welchol has been shown to not reduce cardiac events too. not sure. I am on Repatha. Third bi weekly shot.
The significance of high score is the risk of rupture of the soft plaque into the blood flow channel and cause a heart attack. The score may represent degree of plaque in the left anterior artery
Left main artery with 20-30% narrowing with hard plaque is not considered significant asnd should not be any problem. When the vessel is narrowed to 70% or higher, there could be chest pain and therapy would be necessary.
The non-calicified is soft plaque between the vessel lining.
t have good effects to prevent heart attacks. Howeverk, Crestor was shown to reduce plaque and had better results in clinical studies. Also, with the Niaspan, it is known to raise HDL level but HDL is not necessarily protective as they thought. But that study may be skewed because it was done on all cardiac patients.You may want to read about Vytorin there was a problem with it and I can't remember all the details.
It has this ability apparently because it removes the excess not used by cells and in the brain. It also went on to explain how plaque can also be removed naturally by the body using certain molecules made to control calcium levels for bone growth/repair. The calcium in the plaque can be broken down and the remaining substances such as damaged red/white blood cells etc can be filtered out safely.
t find the right medicine...Lipitor caused severe muscle weakness, Zetia caused all kind of digestive problems and Pravachol zapped my energy...my count actually went up 30 points while taking WelChol! My doctor is telling me that I have no other choices of medicine to lower my count (total 285, HDL 106 VLDL 21, LDL 188, Triglycerids 106.) My sister is having the same problem so I guess this problem is a family thing. I am really troubled by my doctor's lack of concern.
also be aware that the big decline will be at 48-72 weeks with your hbv mutations and hbeag negative
the difference of fibroscan between 4 and 6 is meanless, you have nothing to worry
you may try to see if intf response can be increased by ezetimibe (zetia) or smvastatin.
Hi,
Anytime there is gingivitis present it is normally from plaque that has formed below the gumline and allowed to accumulate. Did your dentist clean your teeth?
You will need a thorough cleaning when the ulcer heals. It sounds as though the ulcer is an abscess from the plaque.
The best thing you can do is follow the dentist's advice and be gentle, but completely thorough in your brushing. You need to start to floss, too.
My contension would be however that most men by age 60 has some degree of plaque buildup whether symptomatic or not and many may not be on statins that tend to stabilize the plaque. If someone with demonstrated CAD is advised to keep pulse below 120, this advice should also be given to everyone reaching that age. If your max is 165, HR of 120 is only 72% of max, barely into the aerobic training zone.
The CT scan measures the soft plaque, mixture of hard and soft plaque, calcified whatever between the layers of the vessel, and this the beginning of CAD and the test would be helpful. When CAD is advanced it the substance between the vessel layer that ruputures, forms a clot, and the clot breaks away causing a heart attack. This occurrence represents about 90% of the heart attacks. The hard plaque within the lumen represents about 10% of heart attacks.
A CT angiogram scans the anatomy of the coronary vessels and scores the amount of soft plaque within the linings of the vessel. Based on the score there is a predicition of the risk to the individuals to a heart attack. The soft plaque is the condition that poses the highest risk of a heart attack as the soft plaque can break through the inner lining of the vessel and cause a blockage that results in heart attack.
How are you? Glomerular filtration rate or its approximation of the creatinine clearance are measured whenever renal disease is suspected or careful dosing of nephrotoxic drugs is required. The normal ranges of GFR, adjusted for body surface area for males is 70 ± 14 mL/min/m2 (56-84) . Risk factors for kidney disease include diabetes, high blood pressure, family history and older age.
Take care and keep us posted.
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