Xeloda and herceptin
Common Questions and Answers about Xeloda and herceptin
xeloda
Within a month, the breast cancer started in her skin around the site of the node. She now has a red rash (skin mets) in approx half of her chest wall and is getting Chemo (Xeloda) and Herceptin. My question is, the skin is beginning to "harden" around the node removal surgery site. What does this mean? Any other comments on Skin mets would be greatly appreciated.
5KGS AT 5FT HEIGHT, WE ARE TREATING THE METS WHICH HAS GONE TO HER LUNGS AND BONES AND LIVER WITH XELODA 1GRAM TWICE A DAY FOR 14 DAYS, AND THEY SCARED US WITH THE SIDE EFFECTS,BUT WE ARE ALSO GIVING HER HOMEOPATHY. WE ARE GIVING A GOOD NUTRITIONAL DIET ALONG WITH A PROTINEX SUPPLEMENT. ON 5TH OF FEB IS HER APPOINTMENT WITH THE ONCO. I HOPE XELODA HAS ARRESTED THE GROWTH OF CANCER CELLS. IF IT HAS CAN YOU TELL ME HOW MANY CYCLES CAN SHE TAKE WITHOUT IT DOING MUCH HARM.
After my 1st chemo treatment of Docetaxel, Carboplatin and Herceptin (12-wk treatment), I developed a red rash on my hands and arms causing skin peeling and pain. Nothing really bad, just sore and annoying. The rash went away w/in 2 wks, but returned stronger with my 2nd round of chemo last week. Is there any OTC ointment that I can use that will eliminate the redness and soreness?
My body smply could not tolerate the drug and while taking Xeloda I lost more than one pound per day, snd had relentless nausea and terrible pain in my hands and feet. After one three-week cycle my doctor discontinued the Xeloda. I was able to complete treatment with the oxiliplatin. This was in 2004 and I am cancer free today. Ask your mother's doctor for something else. If possible she should not stop chemo until her doctor is certain no trace of cancer remains in her lymph system.
Imagine the receptor as a keyhole and Herceptin as the key. Without a keyhole, the Heceptin cannot work.
Unfortunately, the methods for predicting potential response to Herceptin (Daco/IHC, FISH etc) are imperfect. The landmark studies that support the use of Hercepin in your situation chose women with Her-2 positive tumors as defined by Dako 3+ or FISH positive (greater than 2.2). We are learning that some women with discordant results in Her-2 testing still benefit from Herceptin.
will xeloda given alone treat both tumours in chest wall with mestases in liver.
My sister had chemotherapy and herceptin treatment before and after she had a radical mastectomy last year. She has been experiencing severe joint pain since that time. She lived in South Carolina at the time and has since moved to Texas. Her Oncologist in South Carolina had her on Fentanyl patches after lots of other medications didn’t work. Her new Oncologist insists the joint pain has nothing to do with her cancer or treatments and wants her off the Fentanyl.
I am on Herceptin until the end of the year. I am a forty year-old woman and I have experienced a cessation in my menstrual cycle. Intercourse is very painful, even though I am using Replens. I am still very susceptible to urinary track infections too. My doctor suggested Lubrin, but I have been unable to find Replens or Lubrin in stores around my area. I have no children, but I always thought I might have them. What are my chances that my menstrual cycle might come back?
Dr. put her on Xeloda and Tykerb. She is on a 2 week on, 1 week off cycle. Her side effects have been severe. (i.e dehydration, throwing up, no appetite, mouth sores, nausea, you name it, she has it)
Her last visit to the Dr. (she goes about twice a week) just yesterday, he told her (in her words) that "everything is shrinking, and you'll have to be on this for the rest of your life.
I chose chemo and had taxotere, carboplatin and herceptin to cut my chances of recurrance. It was not pleasant, but I am nearly back to my normal self since the end of the taxotere and carboplatin part of the treatment in early March. I worked throughout and have enough hair back to go without a scarf or wig. I am continuing herceptin for a full year and taking tamoxifen for 5 years.
Hand-foot syndrome is a condition where the palms of the hands and soles of the feet become reddish, swollen and develop pain and tingling sensations. Sometimes, rash or peeling of the skin in the palms and soles also occur. Reducing the dose of Xeloda can help decrease this side effect. Applying ice packs and skin lotion can also help relieve the burning sensation and dryness. Another option which your grandmother can take is to discontinue Xeloda altogether.
I have gone through a bilateral mastectomy and 6 months of chemo (5fu andmethotrexate) and now my oncologist suggest herceptin. This is goning to be tough for me to get to since the hospital is an hour away and my job is changing in January. This will mean a half day away from work every three weeks. I was BRCA negative, not genetically caused, had a small cancer removed from my left breast and one lymph node with cancer removed. I am 52 and relatively healthy otherwise.
If your mother is HEr2 positive, then it is better for her to receive Herceptin as this has proven to result in lesser disease recurrence and longer survival. However, if Her2 negative, Herceptin is not warranted (as this would not have an effect on these Her2 negative tumors). I suggest you discuss this with your oncologist, especially Her2Neu testing. Regards and God bless...
With any Her2+ breast cancer, herceptin is recommended as it is highly aggressive, even in stage 1 and small tumors (less than 1 cm.) There have been a couple of studies that have found the recurrence rate (even when tumor is small) can be as high as 23% when chemo and herceptin is not given. With chemo alone, I think the recurrence rate was about 12-13% Herceptin use cuts that down even more to about 7%.
I have heart complications related to chemo--A/C, Taxol, and Herceptin. My LVEF changed from 67% prior to treatment, to 60% to 50%. I am on beta blockers (Carvedilol) and have suspended Herceptin. I want to be pro-active restoring what I can of my heart capacity. What are the excercise recommendations under these conditions. I've been doing strength and resistence training 3 days a week for the last 4 months (to regain muscle strength, etc. lost during cancer treatment).
s cancer is HER2 positive then the administration of Herceptin will certainly give her the very best chance for survival and lessen the chance of recurrance. Perhaps the Her2 test was not completed when only Chemotherapy was recommended. I don't see why the Her2 test done would be in error. Regards....
I was treated with cytoxin and taxotere and now receiving Herceptin. I have had five treatments with Herceptin. My MUGA scan pre chemo and herceptin showed 77.7%. Now after these treatments I have dropped to 61%. I am not overweight, but do have some cardio risk factors, i.e smoking, high blood presure and high cholesteral, also a family history (father) of heart disease.
Should I continue the Herceptin? Have frequent MUGA tests? See a cardiologist?
I am am on dose dense regimine, with round 2 coming up tomorrow. I will have the surgery in june followed by treatment along with herceptin, and finally radiation.
I would inquire with your oncologist if herceptin would be good for you. I do know that they just recently started using it as normal treatment for her2+ . I was told that I would be on it for atleast a year after radiation.
Please let me know what they suggest for you.
By the way six years out AWESOME!!!!!
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