The response to Zoomergirl's question regarding wellbutrin and
buspar in combination is completely innacurate. Wellbutrin
works on the noradrenergic and
dopaminergic system through modulation and reuptake inhibition, and does not work at all on the serotonergic system directly. In addition, it's effects are presynaptic, and not directly at the receptor level. Buspirone, by contrast, is a serotonin 1a receptor agonist, directly stimulating that receptor.