Warfarin and grapefruit

Common Questions and Answers about Warfarin and grapefruit

jantoven

So, I just poured myself a glass of grapefruit juice and took my medicine - then for some reason I remembered that grapefruit juice interacts with some medications. I just did a quick search online and here is a list (probably not complete) of some medications that interact badly with grapefruit juice. Including some opiates.... Please be careful! a small part of the piece I read: "Amy Karch, R.N., M.S.
We just go a some nice Grapefruit form Oregon and I had a couple of slices. Yes I recalled something about not eating or drinking grapefruit juice close to the time one takes a statin drug. I had the grapefruit in morning, and I take my simvistatin about 10 PM. Then I wondered about my Beta Blocker and Calcium Channel. Looking up on the web it said not to eat or drink grapefruit, orange, and some other fruits when taking BB/CCB... said something to about some cancer drugs.
Grapefruit or grapefruit supplements are a no no on tx from everythng I have read. Other will echo this as well.
Often when someone starts taking warfarin they have their blood checked weekly and sometimes more frequently until doctors can find the right dose and patients get in the habit of taking the medication at a scheduled time and control their diet (for example, we routinely tell patients to only eat leafy green vegetables on certain days while taking warfarin and to avoid certain foods like grapefruit completely).
I am currently taking 10mg of coumadin a day and am interested in trying a liver/gall bladder cleanse. It involves fasting,taking epsom salts orally with grapefruit and olive oil. Will the epsom salt have an effect or cause a reaction with the anticoagulant?
It is interesting that twopack mentions 'Supplementing with cranberry juice' , following my husbands triple bypass he was advised not to drink cranberry juice; also no grapefruit or grapefruit juice can be taken with some of his heart tablets.
I have a St. Jude mechanical mitral valve, installed in 1995. Because of blood clots, I have subsequently had a mild heart attack and mild stroke caused from blood clots. I go in for protime test every two weeks as my inr is very unstable. (My stroke happened the day after my inr tested at 2.5. At the emergency room next day, it was 1.7. (My "normal" inr has now been set at 3.5 - 4.
, itraconazole), clarithromycin, nefazodone, diltiazem, verapamil, protease inhibitors (e.g., indinavir). Do not eat grapefruit or drink grapefruit juice unless your doctor instructs you otherwise. Do not start or stop any medicine without doctor or pharmacist approval. ************************************************************ Here's info on "Statin" drugs (Zocor is a statin drug). This came from: http://promini.medscape.com/drugdb/general_drug_adverse_effects.asp?
I am a 29 yr old female I have been on warfarin since feb 09. I had a long flight in nov 08 and I was on estrogen therapy as well as smoking (bad habit I know) and by long flight I mean, comming home from Iraq and wearing combat boots the entire time. I ended up in the hospital with 3 blood clots in my lungs. 2 in my left and 1 in the right. I currently take approx 75mg of warfarin a week I rarely eat leafy green veges. So much so that they have had to put me on iron pills for anemia.
After crying for a few hours, I thanked the doctor for nothing, and told him the pain would be back. A week after the surgery, I was back in another hospital with a grapefruit sized blood clot in my lower right abdomen hmmmmmm. With intravenus warfarin treatment for a week, I went home again. Now here it is, almost 3 years after my "hysterectomy cure", I'm still having the same pain.
alcohol, nicotine, cannabis, amphetamines, Amitriptyline, Celebrex, Cipramil, Lexapro, Codeine, Valium, Warfarin, Dilantin, Efexor, Feldene, Brufen, grapefruit, Luvox, Aropax, Prednisone, Prozac, Serzone, Risperdal, Tegretol, Voltaren, Zoloft and Zyprexa. As I understand it, there are some 50 genes, which determine a similar number of cytochromes, and so a persons genetic makeup will determine if and how such drugs are metabolised.
Dear Robert, It is possible for jumps in the INR to occur and this is why careful monitoring is important. Atenolol may interact with coumadin (generic warfarin). Common foods such as grapefruit juice, leafy green vegetables and many drugs can also change coumadin levels. Smoking also changes drug levels. The following is information on warfarin and it's drug interactions. Coumadin (generic name Warfarin) is a anticoagulant (blood thinner) that is used for a variety of conditions.
Sorry to read you have such a difficult time with medicines (drugs). I generally find I have typical to no side-effects, and, sad to say, minimal benefits. My experience with beta blocker is it does make me tired/fatigue, but I do not require more sleep. I am an old guy too, that doesn't help much with my energy/enthusiasm deficit. On implementation of drugs, my cardiologist and the EP had me on a wearable monitor when I started Rhythmol and would required a hospital stay to start Flec.
Edward Lefrak on January 23, 1996. I had a St. Jude Mechanical valve placed. I am Warfarin resistant. I take 23.5 mg of Coumadin per day to maintain an INR of between 2.5 and 3.5. I had to be hospitalized twice in the first 6 months post surgery. Once for a Basal Ganglion Infarction, from which I recovered completely and once simply to be placed on Heparin due to a low INR. I have been ok since then. I would like to get rid of this valve. Are there any other options availible to me?
The following is information on warfarin and it's drug interactions. Coumadin (generic name Warfarin) is a anticoagulant (blood thinner) that is used for a variety of conditions. Common reasons for coumadin use are in atrial fibrillation to reduce the risk of stroke, in persons with clotting disorders, in persons with mechanical heart valves, and sometimes in people with severe heart failure. The usual dosage is somewhere between 1 and 15 mg a day.
The following is information on warfarin and it's drug interactions. Coumadin (generic name Warfarin) is a anticoagulant (blood thinner) that is used for a variety of conditions. Common reasons for coumadin use are in atrial fibrillation to reduce the risk of stroke, in persons with clotting disorders, in persons with mechanical heart valves, and sometimes in people with severe heart failure. The usual dosage is somewhere between 1 and 15 mg a day.
Grapefruits and oranges are high in hesperidin your diet is the foundation of your nutritional health.This is also true in preventing heart attacks and strokes. A high intake of omega-6 fats, trans fats,and red meats greatly increases your risk.Omega-3 oils, such as DHA with some EPA, significantly reduce your risk of developing cardiovascular disease. Drinking fluoridated water also increases risk, because it contains high levels of fluoroaluminum, a powerful poison.
Do you know: anything about this? Thank-you for your information. : : : : : : I will let an MD answer your questions, but my dad has been on Coumadin for 4 years without any problems whatsoever. In fact, his physician says he's the best patient he's ever had as far as controlling his Pro Time level. Don't be afraid of the coumadin, just be careful with it. My dad does anything he wants to, just watches what he eats so he gets no interactions with food.
It's not the 'earthworm' factor but rather the fact that I'm on Coumadin/warfarin for life now and Bolouke would be dangerous for me to take since I'd be taking two blood 'thinners'. Many sites claim it's safe with Coumadin (mostly sellers or blogs) but I prefer to err on the side of caution. PubMed had only a couple of articles re: blood clots and lumbrokinase.
between diabetes and watching blood sugar levels, and taking the blood thinner warfarin because of the a-fib, and a statin ( no grapefruit). For every yay, there's a nay. I was wondering if anyone out there feels like the palps build up over a few days and then they break into an episode of a-fib or some other equally aggraving arrhythmia? After my a-fib is over I feel free for several days, really goood, till the whole cycle starts all over again. Does anyone else sense that?
Never take any medications or vitamins or herbs with grapefruit juice or antacids. Grapefruit juice can litterally incrase the strength of medications. Antacids can render them ineffective. Its not enough to hear or see natural. You have to know what your taking and how, when and what to take them. READ YOUR LABELS! DO NOT DOUBLE OR TRIPLE ANY VITAMIN, MINERAL OR HERBS! Normally a good quality food based multivitamin/mineral supplement is sufficient.
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