Warfarin and grapefruit

Common Questions and Answers about Warfarin and grapefruit

jantoven

So, I just poured myself a glass of grapefruit juice and took my medicine - then for some reason I remembered that grapefruit juice interacts with some medications. I just did a quick search online and here is a list (probably not complete) of some medications that interact badly with grapefruit juice. Including some opiates.... Please be careful! a small part of the piece I read: "Amy Karch, R.N., M.S.
My wife is on Tenormin for AF and also warfarin, and for the past few months Femara because she has breast cancer. They say Grapefruit juice has an affect on her INR and they recommend not to eat it, but haven't heard anything about a reaction to tenormin. She is of german origin, so naturally ignores everything and drinks a glass of grapefruit juice each morning. Doesn't seem to have had any measurable affect on anything.
Some anti-depressants and a few others don't do well with grapefruit. I am taking Cymbalta and we'll just see what happens. It wasn't listed and my doctor said it would be ok. We will see. If I understood correctly, grapefruit will enhance or build up the drugs in your blood. So, if your on high blood pressure meds for instance, it could cause it to go down too much. If your on a high dose of anti dep. you could get too much. Someone correct me if I'm wrong.
Those clots can shot straight up through the carotid artery to the brain where they can occlude arteries and cause strokes. Or, they can increase back-pressure and cause rupture (bleeding) of a vessel that has been weakened by years of hypertension. I'm not trying to scare you. Only pointing out the importance of controlling A-fib and that there is a total picture that includes more than just tight cholesterol control.
Often when someone starts taking warfarin they have their blood checked weekly and sometimes more frequently until doctors can find the right dose and patients get in the habit of taking the medication at a scheduled time and control their diet (for example, we routinely tell patients to only eat leafy green vegetables on certain days while taking warfarin and to avoid certain foods like grapefruit completely).
I am a 46 year old women who just had a Porcine Tissue Heart Mitral Valve from Edwards Lifesciences installed in August 2001. I am also taking Warfarin 5 mg a day and having test done every 2 weeks. I noticed twice I was told to cut back 2 times a week to 2.5 mg and take the 5 mg all other days when my INR was over 3.5. I have been pretty steady now at between 2.1 ans 1.7 and staying on 5mg a day.
To tell you the truth, there's nothing left that I can eat....between diabetes and watching blood sugar levels, and taking the blood thinner warfarin because of the a-fib, and a statin ( no grapefruit). For every yay, there's a nay. I was wondering if anyone out there feels like the palps build up over a few days and then they break into an episode of a-fib or some other equally aggraving arrhythmia?
With Coumadin, do not start or change the dosage of any drug, vitamin or herbal product without checking with your doctor or pharmacist. Warfarin intercats with many pprescription and non prescription drugs, vitamins and herbal products. The interaction with warfarin usually results in an increase or decrease in the blood thinning or anticoagulant effect. Your doctor or other health care professional should closely monitor you to prevent serious bleeding or clotting problems.
You need to avoid foods and drugs that are also blood thinners such as asprin, advil, NSAIDs, Aleve, Orudis, and other pain killers. Only take what your doctor suggests for you to take for pain and nothing else. You need to reduce Vitamin K because it interveres with the absorbtion of Coumadin. Don't eat leafy greens like broccoli, cabbage, brussel sprouts, or spinich, etc. Don't eat liver or other organ meats. Don't take vitamins or herbal supplements without telling your doctor.
In light of the fact that I am currently UND and have no virus, the reversal of fatty liver and less necrosis and less HCC all sounds very appealing, not to mention any reduction in IR would mean ones own Interferon response would be better post tx. and this alone may increase ones chances of an SVR even if begun at the end of an SOC regime. Perhaps now, more than any other time it could help insure one will recognize any lingering HCV and seek and destroy as designed.
Till that time, you can take foods rich in vitamin C especially the citrus fruits like oranges, papaya, grapefruit, raspberries, blueberries, cranberries, and pineapple. Avoid taking any drugs like aspirin, ibuprofen, or warfarin because these drugs interfere with platelet function or blood clotting. Use adequate sun protection measures, including sunscreen application and sun-protective clothing to protect their skin from further photodamage.
I have been to about 30 doctors- including ENT's allergists, neurologists, chiropracters, opthamologists. psychologists, dentists and everything else u can think of. All CT scans, MRI of brain and blood work keep coming back clean and ok. Nothing I try seems to work. There was a period of time about 3 and a half years ago that the symptoms lifted for about 4 months and then it returned full force.
Three years ago I had angioplasty (lucky me! So far so good - no heart damage) and the docs put me on 20mg Zocor once a day and one 325 Ecotrin once a day. I am now at 160 to 175. Docs monitor my "blood work" at least annually and all is 'normal' except bilirubin is 1.2. Bilirubin had been normal at last test a year ago. Bilirubin had been higher at other tests over the last 20 years, even well before taking cholesterol lowering therapies. It fluctuates.
alcohol, nicotine, cannabis, amphetamines, Amitriptyline, Celebrex, Cipramil, Lexapro, Codeine, Valium, Warfarin, Dilantin, Efexor, Feldene, Brufen, grapefruit, Luvox, Aropax, Prednisone, Prozac, Serzone, Risperdal, Tegretol, Voltaren, Zoloft and Zyprexa. As I understand it, there are some 50 genes, which determine a similar number of cytochromes, and so a persons genetic makeup will determine if and how such drugs are metabolised.
A week after the surgery, I was back in another hospital with a grapefruit sized blood clot in my lower right abdomen hmmmmmm. With intravenus warfarin treatment for a week, I went home again. Now here it is, almost 3 years after my "hysterectomy cure", I'm still having the same pain. I'm starting to think the only real cure will be when I walk into the emergency department, ensure them I'm not trying to commit suicide, and starting my own ovary removal surgery.
Sorry to read you have such a difficult time with medicines (drugs). I generally find I have typical to no side-effects, and, sad to say, minimal benefits. My experience with beta blocker is it does make me tired/fatigue, but I do not require more sleep. I am an old guy too, that doesn't help much with my energy/enthusiasm deficit. On implementation of drugs, my cardiologist and the EP had me on a wearable monitor when I started Rhythmol and would required a hospital stay to start Flec.
The following is information on warfarin and it's drug interactions. Coumadin (generic name Warfarin) is a anticoagulant (blood thinner) that is used for a variety of conditions. Common reasons for coumadin use are in atrial fibrillation to reduce the risk of stroke, in persons with clotting disorders, in persons with mechanical heart valves, and sometimes in people with severe heart failure. The usual dosage is somewhere between 1 and 15 mg a day.
Also be sure to take the same brand of drug each time and always take the drug at the same time of day (usually 6pm). The following is information on warfarin and it's drug interactions. Coumadin (generic name Warfarin) is a anticoagulant (blood thinner) that is used for a variety of conditions.
Also be sure to take the same brand of drug each time and always take the drug at the same time of day (usually 6pm). The following is information on warfarin and it's drug interactions. Coumadin (generic name Warfarin) is a anticoagulant (blood thinner) that is used for a variety of conditions.
Earthworm powder. It's not the 'earthworm' factor but rather the fact that I'm on Coumadin/warfarin for life now and Bolouke would be dangerous for me to take since I'd be taking two blood 'thinners'. Many sites claim it's safe with Coumadin (mostly sellers or blogs) but I prefer to err on the side of caution. PubMed had only a couple of articles re: blood clots and lumbrokinase.
Also be sure to take the same brand of drug each time and always take the drug at the same time of day (usually 6pm). The following is information on warfarin and it's drug interactions. Coumadin (generic name Warfarin) is a anticoagulant (blood thinner) that is used for a variety of conditions.
The following is information on warfarin and it's drug interactions. Coumadin (generic name Warfarin) is a anticoagulant (blood thinner) that is used for a variety of conditions. Common reasons for coumadin use are in atrial fibrillation to reduce the risk of stroke, in persons with clotting disorders, in persons with mechanical heart valves, and sometimes in people with severe heart failure. The usual dosage is somewhere between 1 and 15 mg a day.
They had put me on Warfarin as well as a heart rhythm ...the SR stuff. I had a cardioversion done a month later and right away I could tell the difference between in and out of sinus and the calmness when in as well as how much easier it was to breath. I was in for around a week and one night I could feel it coming, and I was out. I was switched to Taxtia XT 300mg per day and had another cardioversion done, and that lasted maybe 2 weeks, and then back out again.
Thanks to Duchess47, Wepst and JDanMan for your comments and suggestions. I will seriously look into all of your suggestions and hope that it's just some seasonal allergy thing. Thanks again.
Some of us have already been through multiple rounds together, facing this roller-coaster with fearless optimism, and I have been so uplifted by the ladies' kindness, knowledge, and understanding. We invite you to join in.... We are here because we know it will be our turn soon!
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