Warfarin and edema

Common Questions and Answers about Warfarin and edema

jantoven

Hi... My mother is 85 and develops from time to time mild to severe edema in her lower legs, but mostly ankles and feet that subside after 1-2 weeks. In recent months, this cyclic development is accompanied by signs of under-skin bleeding (red & violet patches) in both feet that last even after the edema is mostly gone. Can someone tell me the cause(s), and which doctor I should take her to considering her age and impaired mobility.
Went on Warfarin and then had a failed cardioversion. Went on Amiodarione and had a 2nd failed cardioversion. Was taken off the Warfarin and Amiodarone and told my AF is permanent and ablation unlikely to work either. Half the time I feel kind of OK ... then I get a few 'bad days' when I feel so dizzy and faint with mild tinnitus in both ears and edema in both feet/ankles. I just lie on bed most of the time until it passes.
They insisted at this juncture to put in a pacemaker and put her on Metoprolol, Warfarin, CartiaXT (cardizem), and her usual Norvasc and Atakan. Since this episode and these medications, she has experienced extreme swelling of the lower extremities and now a painful tingling that starts in the late afternoon each and every day and no exercise diminishes the swelling, so she puts them up.
Got his pacemaker/defib and was feeling better but he still has on and off edema issues, is on warfarin, and now that my mom has passed, the depression has affected his heart. Doc says he's fine but that's after I told him don't wait until 6 months to see a doc. I wish you luck.
Of course she's now prohibited from eating a lot of the vegetables that might otherwise help with her bowel problems, due to the drug's conflicts with Vitamin K. She has really bad swelling in her legs, from the knees down, including her ankles and feet. Since her Coumadin dosage was doubled due to low INR levels about 6 months ago, the swelling has gotten worse. I understand that correlation is not causation, but is this common?
You have a lot going on in your body that could make you feel bad, beside taking warfarin, and the warfarin is probably the least likely culprit. The amount of warfarin that any given individual has to take to stay within an INR range of 2.0 to 3.0 (which is probably what the doctors mean when they tell you they want you at 2.5) will vary, depending on how rapidly that person's body can metabolize and excrete the warfarin.
The most unfavorable results in lab were Neutrophils% 86.1, Lymphocytes% 10.1 Lymphocytes# 0.7. The Dr. there just considered hypertension and edema and given drug prescription for BP and edema. I know it is more than that. Did not take med (Enalapril/Hetz 5/12.5)). Who should I see FIRST--a gastroenterologist, kinesthesiologist, cardiologist for this problem? Could the Vagus nerve be affected from the hiatal hernia and the activity pressure?
You should be on long term warfarin with a history of DVT and now pulmonary emboli. By the echo your pulmonary artery pressure is minimally elevated. The echo should be monitored for further changes in the PA pressure and right heart function. You have mild orthostatic hypotension which may be secondary to your recent illness. This should be monitored and potentially thigh length support hose might be of value. If you are not getting the answers you need --get a second opinion.
It is also more common in patients on anticoagulants, especially aspirin and warfarin. Patients on these medications can have a subdural hematoma with a minor injury and it is abnormal localized collection of blood in which the blood is usually clotted or partially clotted.. The treatment of a hematoma depends on its location and size. Treatment can involve draining the accumulated blood.
with aspirin) and/or blood factors that influence clotting (i.e. warfarin). Your mother is taking both aspiring and warfarin which means that she may have an associated history of coronary disease (and aspirin is being used to prevent further blockages to the coronaries or blood vessels supplying the heart muscle) or that she is considered to be at a very high risk of stroke (perhaps due to her age, EF of 25% and Afib) and warfarin by itself isn’t enough.
After three weeks her episodes returned to 4 weekly. All occurred with activity and were relieved by rest and sublingual nitro. Her daily medications include Digoxin 0.125 mg, Furosemide 40 mg, Warfarin 5 mg, Lovastatin 20 mg at HS. Captopril 12.5 mg. KCL 20 mEq BID, and the nitroglycerine described above. We are to describe the pharmacological treatments present in this persons treatment plan.
This is not a new entry - I copied it from my earlier post so I can find it easier when people write and ask me about my symptoms. MS or NOT? From my medical record and tests- Female, 53 years old. Myocardial infarct January 2008. History of tobacco and alcohol use. I have since quit everything, including caffeine and chocolate. This is not associated with arterial disease, because my arteries are not clogged.
, longer than about a week) or high-dose corticosteroid therapy should have blood pressure, electrolyte levels, and body weight monitored regularly, and be observed for the development of edema and congestive heart failure. The dosages of antihypertensive medications may require adjustment.
Is anemic, has leg edema, has had multiple transufiions, on multiple drugs including folvite, amiodarone, acitrom (like warfarin), clopidogrel, metolazone, Livogen (B Complex Vitamin formulation), and rabeprazole who has loose watery stools often in the bed without the knowledge of soiling the clothes. I suspect he has c. diff. b'cos of multiple drugs. Please advise how this should be treated.
The corpus callosum is normal in morphology and signal. The cerebellum and brainstem are norman in strcture and signal. No evidence of cortical infarct, intracranial hemorrhage, edema, mass lesion, abnormal, enhancement, or abnormal extraaxial fluid collection. The ventricles are normal and at midline. The paranasal sinuses and the arterial flow voids are patent. No chiari malformation.
Her leg is getting sore again, and she is wondering if there is another blood clot forming and if it could be caused from the chemo. Thank you for taking the time to read and answer my questions. I appreciate it!!!
coumarin intoxication is suggested based on - Diffuse subcutaneous patchy haemorrhage. - Submucosal edema and haemorrhage of gall bladder. - Severe splenic haemorrhage. - Severe mucosal haemorrhage of colon. - Severe lung congestion Pathologist final comments: Intoxication of Warfarin/Coumarin and Derivatives. Please comment from my first post as well as having this information you should be able to come up with a conclusion based on my story as well as autopsy report.
I have not been officially diagnosed with AFIB, but I have heart palpitations and I am pretty sure that is what is going on, I also have the edema and tachycardia (3 years now), I have been on Toprol and HCTZ for the edema. Never had an answer as to why, but now the Dilated left atrium makes sense and all of the puzzle pieces seem to fit! Do you exercise? What kind do you do? I am taking all kinds of suplements and changing my diet and no more caffeine!!
Docs found on my ankle MRI 1) Marked subcutaneous edema of the distal lower leg and ankle. 2) fluid present within the flexor hallucis longus tendon sheath. The fluid extends along the plantar surface of the tendon as it progresses towards the insertion of the hallux. 3) Degenerative changes within the hindfoot. 4) Subchondral cyst is present as well as adjacent cyst within the sustentaculum tali at the level of the medial subtalar joint. Diagnosis: Tenosynovitis of flexor hallucis longus.
coumarin intoxication is suggested based on - Diffuse subcutaneous patchy haemorrhage. - Submucosal edema and haemorrhage of gall bladder. - Severe splenic haemorrhage. - Severe mucosal haemorrhage of colon. - Severe lung congestion Pathologist final comments: Intoxication of Warfarin/Coumarin and Derivatives. Please comment from my first post as well as having this information you should be able to come up with a conclusion based on my story as well as autopsy report.
A clot already present must be treated with Heparin or Warfarin ( thrombolytics or blood thinners) and not Aspirin. Aspirin is only prescribed for prevention of clotting. Once the clot has formed Aspirin is of little use. Please take treatment for the clot immediately otherwise it may lead to multiple strokes. Lesions on the MRI may be suggestive of MS. It may not be diagnosed on a single MRI. A series of diagnostic tests may be required to rule out the disease.
I need some answers to the severity of this condition. I feel that my primary care physician and the members of his staff and group where very neglectful in this matter. any advice would be appreciated in regards to filing a case against them for there neglect to inform me of this (EF) report.
It is coming to the end of the semester and there are obviously deadlines looming etc and I am a naturally anxious person but I have never had this kind of anxiety. My heart feels like it's thudding all the time in my chest at night and it feels faster. Last night I only managed 3 and a half hours of sleep even though I was absolutely shattered because my heart was thudding so much and I was extremely anxious. I'm pretty sure this is to do with the provigil.
An irregular rhythm compromises the heart's ability to pump blood effectively and fluid can build up in the lungs (pulmonary edema). A medication to prevent blood clots (warfarin) is important too. Heart disease and diabetes are two chronic conditions that can be effectively managed for years to come. The quality of life is dependent on management of troublesome symptoms like fluid build up in lungs and legs that challenge breathing and mobility.
I am an 81 year old male, had double-bypass surgery with aortic valve replaced over 3 years ago. Heart has been in A-Fib, since surgery, and on warfarin, but able to live a normal life, and participated in a cardio exercise class 3 times a week. Six months ago my echocardiogram ejection rate was 58%. I was fine until Oct. 2010, when I began feeling very tired, & noticed the beginning of edema in my feet and lower legs. In Jan.
Was doing quite well until a few months back when a CT showed pleural effusion. Echo was done and he was put on a diuretic to get rid of the edema ... and was recently taken off the diuretic after a followup CT had good results. Echo indicated that he's developed valve disease (mild to moderate mitral regurgitation with moderate to severe tricuspid regurgitation and moderate pulmonic regurgitation) and for the first time, moderate CHF (LVEF 35%) ... previous LVEFs had always been in the 50's).
coumarin intoxication is suggested based on - Diffuse subcutaneous patchy haemorrhage. - Submucosal edema and haemorrhage of gall bladder. - Severe splenic haemorrhage. - Severe mucosal haemorrhage of colon. - Severe lung congestion Pathologist final comments: Intoxication of Warfarin/Coumarin and Derivatives. Please comment from my first post as well as having this information you should be able to come up with a conclusion based on my story as well as autopsy report.
While no specific answer came up, I did learn that there is a very small percentage (0.01%) of people who are considered warfarin resistant, and this is due to a genetic abnormality. The other interesting thing that I learned is that there are some people who have varying INRs due to malaborption issues due to the interaction of oral anticoagulants with drugs and food.
Within 2 weeks of being discharged he had a 7lb wgt gain and had fluid drain as an outpatient. He has been taking Lasix and taking classes and following a "CHF diet" watching salt and fluid intake. His weight has remained stable. He still has SOB upon limited exertion and would like to be able to continue his "pre CHF" 3 mile daily walks. this week his RBC 3.9 H/H 10.9/31 BUN/Cr 42/1.5. He has been taking iron and folic acid for 6 weeks.
Oh, yes, the reason I was at this site in the first place was to ask someone if coumadin (warfarin sodium) could be responsible for the destruction of red blood cells with the concommitant buildup of fluid (edema) in the body, for which Lasix and a transfusion were prescribed for one of my dearest friends. That is what he was told, and since I am on Coumadin also, he sent the information on to me. Thanks for any help.
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