I think that some drugs have been held up (re-visit the morning after pill in the abstinence era), some have been approved too easily (my father died after being treated with Vioxx
, but before the recall broke). This is not a organization that always does things right. Approving the wholesale use of the drug for past treatment failures or at the minimum for compassionate use could save many lives. It is pretty much a no-brainer that many lives would be saved.