Vioxx heart problems

Common Questions and Answers about Vioxx heart problems

vioxx

I am a 48 year old female. Although I have always felt, on occasion, a "skipped" heart beat followed by a strong beat sensation, this past weekend I was unable to sleep much due this occurring constantly when I would lay down and, although much less, while getting up, walking around and sitting down. It scared me to death so I went to my Doctor yesterday. When I would lay on my left side she was able to hear it and called it a "premature beat".
I have been having problems with my heart for the last 4 years of my life.The skips and extra beats have only gotten worse..I have had two echocardiograms,countless ekgs, 2 holters and a event monitor.Im still waiting on the results of the event monitor..but considering my apt isnt for almost 2 months im taking it they dont think its too bad.Im on atenolol 100 milligrams a day..50 in the day time and 50 at night for my racing heart.
Nobody's ever had problems with it before. Vioxx and Celebrex inhibit Cox 2. Ibuprofen is non-specific and inhibits Cox 1 mostly and slightly Cox 2. Cox 2 is where the risk comes in. I'm still going to take it. Pretty soon they're going to tell us that aspirin is dangerous. Ha Ha!!!
39 yr old female, 15 pounds over weight, blood pressure fine, cholesterol fine, no other health problems, no family history of heart problems, smoker for past 7 years. About 6 weeks ago I had a heart attack with 90% blockage LAD. A stent was placed and I was put on blood pressure med, cholesterold med, plavix as well as a few other meds. About a week to 10 tens after the heart attack, I began having brief periods of shortness of breath.
Not to be confused by your answer, does the resting heart (BPM) go lower with age? 2.I seldom experience a stronger heart beat, from what I understand a pause followed by a stronger heart beat resulting from larger blood flow. I've been tested 3 times with a holter and found a resting rate at sleep of 35BPM and a pause of 2.2sec being the longest (1 PVC). My questin is related to PAC's & PVC's.
But if it gets back to being almost every day, I can't imagine having to continue to deal with that for the rest of my life. As long as the bone is in place, I have no problems. No swallowing problems, no pain, nothing. I just never know when it's going to pop. I do a lot of public speaking and presentations. My greatest fear is that it will happen in front of an audience. The pain is so sudden and intense that I immediatley burst into tears.
Celebrex is the only medication that does not go down the COX-1 pathway very much. Others were developed (Vioxx and Bextra), but then recalled due to issues with people having heart problems. So, if you do not have GI bleeding or an ulcer, you may want to ask your doctor about other NSAIDS. Mobic (the generic name is meloxicam) is a great alternative, because it is generic and has less GI/ulcer problems than most of the NSAIDS. Ultimately, you should see what your doctor thinks is best for you.
Have any of you had a heart abnormality while you've been on treatment? My internal medicine doctor kept on bugging me to get some tests on my heart, since he heard a murmur. I figured it was nothing and that it's just the meds, Riba, etc. Yesterday, I had my exercise stress test. He stopped it after I had completed part of it because I was getting winded and the test showed up saying it was 'significantly positive'.
To get back to the subject at hand, I have heard for quite some time that there are connections between heart problems and people that have thyroid problems. I suffered the symptoms of a MI on April 2nd of this year, and due to the fact I was in denial and neither my husband called 911 or myself, I have been having a hard time getting a definite diagnosis, that I did in fact have a MI.
ischemia (due to blockages - including both stable and unstable angina and acute heart attack and coronary artery spasm), pericarditis (inflammation of the sack around the heart), myocarditis (inflammation of the heart), cardiomyopathy (heart failure) and rarer causes such as coronary artery dissection, acute rupture of the heart and valves and infections of the pericardium.
My mom does not have any heart problems, but when she tried Vioxx for her arthritis she gained 10lbs fast. She got off it and the extra weight disappeared. Just FYI.
These proved much more effective but a danger was uncovered in that patients had an increased likelyhood of heart problems. I was on Vioxx and for the first week I felt likely I had a new body. No more arthiritis, it was great. Vioxx was taken off the shelves last year. It helped me for longer than that but so obvious the first week. In place of that I have tried the others that were competitors to Vioxx like Celebrex and two others but they dont help me.
Anyway, referring to what I mentioned to JudyW--the hematologist/oncologist I went to last month at first laughed at what I told him about the study on Vioxx. He said Vioxx is what the docs avoid when you have low platelets and started describing how it causes platelet problems. But when I went to the follow up visit, I had the report that I had seen on this forum with me and showed it to him and he spent a long time reading it completely.
People with diabetes are unable to properly break down carbohydrates, either because their bodies do not produce enough insulin or because of resistance to insulin. They are at higher risk for heart attacks, kidney problems, blindness and other serious complications. Avandia was Glaxo's third best-selling drug in 2006 with U.S. revenue of $2.2 billion, according to health care statistics firm IMS Health.
before reqesting medicine from my orthopedic surgeon i did research online about vioxx and celebrex. i saw online for myself that vioxx had a high number of heart problems in people...so i went with celebrex. i never took the celebrex though as i am not a medicine taker. plus since i have moderate to severe mitral valve regurgitation i am reluctent to take any medicine that might effect my heart. but i do take ibuprofen when needed for the pain..
I am wondering if the new medications he is putting me on (viox and imitrex) can cause worsening heart problems or effect coumadin levels? I have a very uneasy feeling about this neuro. I deeply respect my other doctors, but I am not sure about him. My doctors think I am having v-tach, not sure whether it is sustained or not, they are recording with my pacemaker.
Last month he had chest pains and a catheterization showed mammary bypass was still open, but blockage was found in 2 smaller left arteries, and 2 cypher stents were successfully implanted. The problem is that his chest pains did not go away. The cardiologist says the heart images show blood is flowing freely, but now believes my husband has an inflammation of the heart which he has called a type of pericarditis.
Volleyball ends in 2 weeks so I can stop the vioxx - hopefully things will settle back down. Has anyone else had problems w/ Nexium & gout?? I have trouble w/ gout anyway...I believe that's what got my stomach into the mess it's in today - all the anti-inflams. It was course of prednesone & vioxx that sent me over the edge. Is there a "kinder, gentler" anti-inflam??
I think people (yeah, ME, the girl who can' t stop the vics), that being aside, you should read the warning leaflet and decide for yourself if the side effects are worth it. I was given vioxx years ago, read the warnings about heart attacks and such, and threw them all in the trash! Not much later it was pulled from the market. If I lost a loved one, $$ isn't going to bring the back anyway, it's all stupid. If I do myself in, I guess I will come back and haunt the manufacturers....
Recently, Vioxx has been removed from the market due to heart-related problems. Celebrex and Bextra are currently being investigated for similar heart-related toxicities. It is recommended that people with liver disease avoid using all NSAIDs. If NSAIDs are medically required for the treatment of another medical disorder, a reduced dose should be used for a limited period of time and only by people with stable liver disease.
Thank you for posting the link to the article about the Vioxx study! I had only seen a brief summary, (started taking Vioxx on that basis alone) and had been looking everywhere for the article without finding it! I've printed it out, now. THANK YOU!!
They did do a doppler echocardiogram with no problems found. 2 days after discontinuing Vioxx, I became symptom free, my BP is back to normal, and I have been fine since. Bottom line: always seek out the best doctor and always get a second opinion before undergoing any invasive or risky proceedures.
Studies have ahown that, while aspirin's platelet effect protects people from heart problems, at the same time study groups have experienced significant increases in hemorrhagic stroke incidence, even with dosages as small as 350 mg every other day. It is thus obvious that the dosage of aspirin, together with intake of other agents which act on platelets just as aspirin does, is an important decision. I take daily doses of Vitamin E and naproxen sodium tabs.
Noticed I always run low and thought because of heart murmurs, mvp But when palps are abundant my b/p and heart rate are up and I am just sitting. Thoughts to share..........
feeling of shoulers being pulled towards each other, and extreme pressure as if someone heavy was sitting on my chest. Taking a deep breath was impossible to bare. Final diagnosis was Costo Condritis,which I was told was inflammation between the joints between the ribs and breast bone,a form of Arthritis. Percocet was given for pain with no relief. I was already taking Vioxx-50mg/day. Need more information on Costo Condritis and TSETSE syndrome.
The problem with extrapolating these trials is that they only looked at 2 specific statin medications when there are several out there. Mevacor is right stating it has been shown that it prevents heart attacks as it was shown to prevent heart attacks in a well designed prospective large trial. Some of the other statin medications can not make the same claims as they have only been tested in safety or soft endpoint trials designed to market the medication.
Oh yea after taking the floxen the heart burn seem to be gone then he put me on prilosec for the heart burn well I dont have that anymore so why take it. He has giving me vioxx for the pain in the tailbone should I be taking all of these meds what can you tell me. Please I am desperate.
What they discovered was that all NSAIDS increased the risk for heart attack and stroke with Vioxx being the worst. The FDA then mandated that the additions of heart attack and stroke be added to all NSAIDS patient information and warnings including Vioxx. The FDA published a Talk Paper and implemented labeling changes for the Vioxx based on the results of the Vigor study.
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