Venlafaxine and amitriptyline

Common Questions and Answers about Venlafaxine and amitriptyline

effexor

I used to take 150mg but reduced it due to palpitations and flashes of lightheadedness and dizziness and palpitations. My doctor thought these were due to anxiety-I didn't and still don't.(the palpitations often woke me up !). All was well for a while - but now they are back again. I can resist having a panic attack on top of the swmptoms, but they are very unpleasant. I also now have some unsteadiness and bad coordination when walking, and would like to stop the drug.
Hi all, this is my first post and I am new to all this to, so please excuse me for lack of etiquette. I would like to know if there is a substitute for amitriptyline first and foremost. Now I know you guys are based in the US so the names of the drug may be different but I really do need some help. I am aware that it is used frequently for people suffering with MS as both pain relief and as an anti-depressant but living with the side affects is daunting.
Venlafaxine was shown to be effective for depression in multiple double blind studies. Venlafaxine is similar in efficacy to the tricyclic antidepressants amitriptyline (Elavil) and imipramine and it was better tolerated than amitriptyline. Venlafaxine appears to have efficacy similar or somewhat better than sertraline (Zoloft) and fluoxetine (Prozac) depending on the criteria and rating scales used.
For my depression I took fluvoxamine 50mg, mianserin 60mg and clonazepam 2mg before sleep for 10 years, after failing single drug therapy. I found Prozac, Citalopram, Sertaline, Paroxetine, Venlafaxine, Mirtazapine, and Monclobemide could not replace Fluvoxamine. It indicates that different SSRIs has different effect on a particular individual. I deny failing prozac and Celexa means the rest of the SSRIs is contraindicated.
Some of the medications used to treat neuropathic pain include antiepileptics such as neurontin and lyrica. Other medications that can be added include antidepressants such as amitriptyline or venlafaxine. There are additional treatment options that include pain medication injections. These are usually performed by anesthesiologists in chronic pain medicine groups.
• the Tricyclic antidepressants such as Amitriptyline (Elavil), Imipramine (Tofranil), and Doxepin (Sinequan) • the Monoamine oxidase inhibitors (MAOIs) such as Tranylcypromine (Parnate), Isocarboxazid (Marplan) and Phenelzine (Nardil) • the Selective serotonin reuptake inhibitors (SSRIs) such as Paroxetine (Paxil) • the atypical anti-depressants such as Mirtazapine (Remeron) and Trazodone.
He put me on Venlafaxine (Effexor) 37.5 mg and increased to 75 mg. But this didn't help and I still woke up tired. I also got dreams in the night which didn't help. Then I saw another doctor who tried out SSRI's but didn't work. Then I was put onto Amitriptyline (Elavil). This helped my sleep. It was wonderful. then I developed OCD symptoms. Earlier I had mild OCD but now it became pronounced.
I am taking 75mg of venlafaxine and 10 mg amitryptiline at night which I have been taken for a couple of months. Why am I feeling like this?
I didn't tell it but they prescribed amitriptyline for anxiety and trazadone for sleep but I just can't seem to take them. They make me like a zombie. My head is all fogged up if I take it and I still don't sleep. Maybe I'll try not taking anything for a week or two and see what happens. I don't feel depressed but feel very anxious and I also don't sleep.
He put me on Venlafaxine (Effexor) 37.5 mg and increased to 75 mg. But this didn't help and I still woke up tired. I also got dreams in the night which didn't help. Then I saw another doctor who tried out SSRI's but didn't work. Then I was put onto Amitriptyline (Elavil). This helped my sleep. It was wonderful. then I developed OCD symptoms. Earlier I had mild OCD but now it became pronounced.
The antidepressants clomipramine (Anafranil) and venlafaxine (Effexor) also help obsessions. The FDA approved Prozac, Luvox and Anafranil as medications beneficial for OCD. The anti-obsessional benefits of any of these medications may not be fully apparent until 5 to 10 weeks after treatment starts. Imipramine, and alprazolam and the mild tranquilizer buspirone (BuSpar) also show some indications of being useful for certain individuals.
Males Venlafaxine Effexor® Anti-depressant / depression Amitriptyline Elavil® Tricyclic Antidepressant / depression Erythromycin Erythrocin® Antibiotic;GI stimulant / bacterial infection; increase GI motility Females>Males Lithium Eskalith® Anti-mania / bipolar disorder Gemifloxacin Factive® Antibiotic / bacterial infection Phentermine Fastin® Appetite suppressant / dieting, weight loss Felbamate Felbatrol® Anti-convulsant / seizure Ofloxacin Floxin® Antibiotic / bacterial i
nortriptyline, amitriptyline, imipramine, desipramine, and fluoxetine phenothiazines (thioridazine) and Type 1C antiarrhythmics propafenone, flecainide, and encainide), or that inhibit this enzyme (quinidine) that according to the FDA should be used with caution in patients taking paxil.
Effexor and Pristiq are 99% the same drug in terms of active chemical. Pristiq being Desvenlafaxine and Effexor being Venlafaxine. In fact if you look at the molecular chart for the two drugs they even bind the same. Funny thing is you know why Weith pharm released Pristiq? (a drug much like Effexor) Because the 7 year patent on Effexor was close to an end and Weith didn't want to lose market share. In comes Pristiq (Name brand only for another 7 years) It's all about the money.
I'm on a generic form of Wellbutrin, thanks to my neuro who decided I was depressed. I didn't argue with him and said I would try it for a while. It is now almost a year later and I'm still taking it. I don't know if it really makes a difference for me - I didn't thnk I was depressed to start with. But I will agree that I don't register a very wide range of emotions - except when I get ticked off.
Went to my NL today and of course another round on the Chiari merry-go-round! He wants me to taper off of the Amitriptyline and start taking 75mg of the herb Butterbur petadolex, continue the 100 mg of Topomax twice a day and add gabapentin 300mg, and then start Botox injections...to try to get rid of my migraine HA's. Even with numbness getting worse in both hands, and legs...all symptoms getting worse btw! I told him that the eye Dr.
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fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), then SNRI Venlafaxine (Effexor). Effexor AND Cymbalta may be more likely to cause side effects or to set off manic episodes or rapid cycling. If all else fails :Mirtazapine (Remeron) Nefazodone (Serzone) Monoamine oxidase inhibitors: phenelzine (Nardil), tranylcypromine (Parnate). These are very effective but also require you to stay on a special diet to avoid dangerous side effects.
If you feel up to it at some point, it may be worth trying out some other options like anticonvulsants such as lyrica (pregabalin), neurotin (gabapentin), or tegretol (carbameprazine I think), or some antidepressants like endep (amitriptyline, a tri-cyclic), effexor (venlafaxine, a NSRI), or prozac. All of these act upon the central nervous system, and all of them have some success at reducing the levels of chronic pain.
Reference to Table 1, Chapter I, which shows the equivalent strengths of different benzodiazepines, should enable you to work out your own programme and to devise an appropriate schedule for benzodiazepines such as prazepam (Centrax) and quazepam (Doral) and others which are not illustrated. In my experience, the only exception to the general rule of slow reduction is triazolam (Halcion).
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