It can be caused by reduced kidney function, chronic kidney disease, congestive heart disease, varicose <span style = 'background-color: #dae8f4'>vein</span>s
, phlebitis, protein or thiamine deficiency, sodium retention, or cancer).
Such kind of features including numbness of hands are also found in diabetes, hypothyroidism, hypoparathyroidism, peripheral vascular disease, vitamin B12 deficiency, malnutrition, carpal tunnel syndrome, transient ischemic attack, moto
r neurone disease, or auto
immune disorders like multiple sclerosis.