Valsartan and losartan

Common Questions and Answers about Valsartan and losartan

diovan

I've been taking 40mg/day Diovan/valsartan recently in addition to beta blockers. I've heard about studies and reports that ARBs such as losartan and valsartan have proven effective in mice to treat aortic aneurysms in Marfan mice and to effectivel 'heal' them. 1.) So this is a general question - in your practice, have you seen beneficial results on human aortic aneurysms using ARBs? 2.
I want to thank whoever it was out there that first posted about Cozaar, Losartan, and valsartan it all sounds promising. My name is Steve and I am a 34 year old male. I was diagnosed at birth with a bicuspid valve. I have never had any symptoms with this and have always had an active normal live. 6'2" 180lbs. Last summer I decided to get a CT done since I hadn't in over 10 years. Well I wish I would have done it sooner as my ct discovered an aneurysm of my ascending aorta of 4.
It is thought that losartan is not as good a choice as other ARBs like valsartan and telmisartan because losartan penetrates tissue less than those drugs and because losartan is a surmountable antagonist that could, theoretically, lose effectiveness over time. This isn't a proven fact to my knowledge and Dr. Dietz for various reasons may or may not agree.
So I would like to know if a dosage of around 25 mg of atenenol, (I take atenenol because I'm a very active person), and a high one of losartan would be a bad combination of the two drugs. Also what is the difference of losartan and valsartan?
My new VA doctor wants to change one of my blood pressure medications from 160 mg of Valsartan 2 times per day to an equivalent dose of 100 mg of Losartan but only once per day. My blood pressure has been controlled for years with typical readings around 118/70 using the Valsartan, Amlodipine 5mg, and a diuretic (hydrochlorothiazide 25mg). I have not made the change yet. 1. Why should I agree to experiment with reducing my primary blood pressure medication and what are the risks?
As you may be aware, there has been enormous excitement in the Marfan community lately based on research originating at Johns Hopkins using ARBs (and in some studies, ACEi's) like losartan to reduce TGF-b signalling and thus arresting or even reversing aortic dilatation.
I went to the doctor yesterday and he took me off the Metoprolol and put me on 100 mg of Losartan. He told me to just stop taking the Metoprolol. I questioned starting off with such a high dose of Losartan. I seem to be very sensitive to these medications and felt starting right off with 100 mg was a bit high. Everything I've read online suggests people are usually started off with 50 mg. I questioned just stopping Metoprolol suddenly. Both questions were fobbed off.
Actually, is Diovan belongs to a class of blood pressure medications called angiotensin II receptor antagonist. It is a combination of Valsartan and the same diuretic as Hyzaar. It is essentially the same as Hyzaar which contains a combination of hydrochlorothiazide and losartan. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
I have been telling people on these boards for a long time to investigate angiotensin receptor-blocker (ARB) (any ARB except losartan is preferable) or ACE-inhibitor (ACE-i) (perindopril is the only one I know of that really works) therapy with a cardiologist at a major medical center/university who is UP TO DATE on the latest research.
Taking coenzyme Q-10 along with medications for high blood pressure might cause your blood pressure to go too low. Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others. • Warfarin (Coumadin) interacts with COENZYME Q-10 Warfarin (Coumadin) is used to slow blood clotting.
Thank you. Meanwhile the meds did not help. I have tried Losartan for 3 weeks and yesteday the doc changed it onto Valsartan.
Research reports favour different ones and contradict each other. Some favour Candesartan, others Losartan; and still others Valsartan. They all have slightly different modes of action. Which would you choose? OR - would you favour a different class of BP meds? CNS; vasodilators; calcium channel blockers etc. Since I had a problem with ACE inhibitor, would I also have a problem with ARBs, given that their modes of action is similar?
Listen, you need to educate yourself on a class of drugs called angiotensin receptor blockers (ARB for short). They include drugs such as losartan, irbesartan, valsartan, telmisartan, etc. (anything ending in "-sartan"). The most cutting-edge studies coming out of Johns Hopkins have shown that these drugs HALT and/or REVERSE aortic root dilatation. It appears that a maximal dose is required. Although you may or may not have Marfan syndrome, I strongly encourage you to visit www.
1 I know I must cut out the heavy and keep breathing steady through my workouts with no breathe holds. I've been on an ACE but switching to Losartan 50mg and will request to go to 100mg based on what I've read. I will be getting a second opinion due to the wide swing in readings two days apart and just to get another prospective. My doc was oblivious to any Losartan studies. Would my theory on inflammation be wishful thinking?
Some other ARBs and ACE inhibitors may work less effectively or not at all (some ARBs I know to be good - besides telmisartan - are valsartan, irbesartan, candesartan. Most of them are good EXCEPT for losartan, which is a surmountable antagonist and, theoretically, would lose its effect over time). Next fact: you need to take a high dose.
ARBs are a class of drugs that have been clinically proven to halt and even reverse aortic root dilatation in humans. They include valsartan, telmisartan, and other drugs that end in -sartan. The key is to take a high enough dosage - for most people, this is about the maximum FDA-approved dose. In particularly large people, the required dose may be higher. You should quickly find a cardiologist who is knowledgeable about connective tissue disease and ARB therapy.
) also reduce blood pressure by dilating the arteries.
angiotensin II receptor antagonists such as candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro), losartan (Cozaar), olmesartan (Benicar), telmisartan (Micardis), and valsartan (Diovan); antacids such as sodium bicarbonate; caffeine (found in certain medications to treat drowsiness and headaches); calcium channel blockers such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, others), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat,
A beta blocker like, atenolol or toprol, and a ARB, like cozaar(losartan)or Diovan(valsartan), a mild durectic like Esidrex(hydrochlorothiazide) all combined might be useful, just a suggestion, get her to ask her doctor about these drugs, they could probably get her B/P under control. Hope you are okay. Take care. Took your advice also.
Angiotensin II Receptor Blockers Telmisartan (Micardis) Eprosartan (Teveten) Irbesartan (Avapro) Valsartan (Diovan) Olmesartan (Benicar) Candesartan (Atacand) Losartan (Cozaar) 5. Antiplatelets Ticlopidine (Ticlid) Clopidogrel (Plavix) 6.
candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro), telmisartan (Micardis), valsartan (Diovan), losartan (Cozaar), and olmesartan (Benicar). ARBs are used for controlling high blood pressure, treating heart failure, and preventing kidney failure in people with diabetes or high blood pressure. They may also prevent diabetes and reduce the risk of stroke in patients with high blood pressure and an enlarged heart. ARBs may also prevent the recurrence of atrial fibrillation.
But I remember that you mentioned your doctor prscribing some ARB medication (losartan or valsartan) to halt liver fibrosis. This could be an important factor in your results. I wonder if there is any chance that you do not have cirrhosis. After my husband's experience with "golden standard" nothing would surprize me, and I sincerely wish this for you. What if during biopsy they just picked the piece that had a lot of damage?
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