For years after having a complete hysterectomy, I was on a gel, Estragel or something like that, where you rubbed the gel on your arm. I was told it was safer than an oral estrogen
or shots
or patches because it didn't have to pass as much drugs through the liver. Also, right after my hysterectomy (which I had at a very young age 30), I did use Testosterone for a VERY short period of time, prior to learning that I had Hep C. After that, I was taken off of it as it is hard on your liver.