tysabri vs rebif

I am another Tysabri user - I will get #48 next week. I started on Rebif first, just like GG. I was on it for 6 months, but I continued to rapidly decline, and was sick all the time from the Rebif. I was shocked when my neuro suggested Tysabri, but after much research and reading, and realistically weighing the risk vs benefit for me, we decided to give it a whirl. I have since found out I'm JC positive, but am continuing with the Tysabri at this point.

) He explained alot about Tysabri - truth vs hype. He is trying to do whatever he can to try to keep me from having more serious disability... he's very concerned apparently. Who knew? :) He has about 18 pts on it for the past 2 yrs... all have either improved or held steady, and these were his worst pts in terms of the MS. They explained some of the TOUCH progam to me.. Needless to say, I have alot of research to do so I can make an informed choice on what is best for me.

My new neuro suggested Tysabri based on increased lesions on Interferon (Rebif). Any persons out there on Tysabri that could share their experience?

My neuro is considering switching me from Rebif to either Tysabri or Novantrone. I started Rebif in Feb 2008, however was not on it long enough to really know if it was doing any good as far as disease progression/relapse reduction, as within 8 weeks my liver enzymes had elevated and my treatment was suspended. I just started Rebif again this week on a very gradual titration schedule, and my liver will be monitored closely via weekly labs.

If so, if your fearful of the Tysabri you can always go to Rebif, which is 44mg, or Betaseron 1ml vs. the 30mgs you are on w/the Avonex. And, there is always the daily Copax, which I'm sure you know has shown to work for some too - though by different mechanism than the interferons. If you stay w/interferons, least your body is already 5 months into them and it would just be an increase and sub-q. Did they treat your ON Jason?

After waiting for insurance to approve and waiting for rebif to clean out of my body I had my first tysabri infusion on June 3rd, 2014. By the next day I could tell that it was easier to get up and my balance seemed better. I didn't notice anything else but was excited about what improvements I would have in the future. I felt the same after infusion #2 but was hoping for more. After my third infusion I had a bad headache for 2 days and didn't feel any improvements.

Hard to answer your question without more information. Why do you have only those four choices? Avonex (which I’ve used for 11 years) and others are notably absent from your list. Avonex, Rebif, and Betaseron have been around longest and have the strongest safety profiles. If your MS is more aggressive, then you may be more inclined to consider Gilenya, Tecfidera, Aubagio, or Tysabri. All of the DMDs are discussed from a neutral perspective at the link below: http://www.nationalmssociety.

I did as much reading and research as I could for the next 3 weeks, and we decided to roll the dice with Tysabri. I was going down fast, Rebif wasn't helping, and my neuro didn't feel that any of the other CRABs would help. My hubby and I felt the risk was worth the potential benefit. I have been on Tysabri ever since - I had infusion #45 yesterday. I am JC virus positive, so I have 2 of the 3 major risk factors, but at this point we are still staying with Tysabri.

( AVONEX, REBIF,COPAXONE BETA, TYSABRI?) I AM ,I HAVE TRIED ALL, GETTING READY TO TRY BETA, MY DOC WONT PUT ME ON TYSABRI, AFTER THIS WHATS NEXT? I DONT WANT TO GIVE UP. I'M SO DEPRESSED I'M AFARID IM GONNA BE ALLERGIC TO BETA THAN WHAT? PENNY K.

Last week I started my 3rd significant relapse this year, my specialist nurse is now talking about Tysabri. I was on Rebif for about 15 months and wasnt getting on with the side effects so I switched to Copaxone 6 weeks ago, which I'm quite happy with. I looked up Tysabri when I got home and all I got was all the bad news about the PML patients. They say that theres a 1/1000 chance of getting it, that seems quite high to me.

A little re-cap on my situation w/meds and an allergic reaction. I had an allergic reaction while on Rebif, Xanax, and Temazapam. My MD and Neuro said they did not feel it was my meds, so this reaction went on for months. I'll not get into all the particulars of symptoms as it will be too lengthy. So, simply stated, I feel it was a drug induced lupus based on my research all that comes with and more. I went to an allergist. She felt it to be Rebif.

Hello James, I am guessing you mean drugs to slow the progression such as Rebif, Copaxone, Avonex and Betaseron . All but Tysabri are reasonably safe which is more affecective in slowing progression in some MS patients. The deal with MS drugs is the better they work at slowing progression the more dangerous they are because at the same time they suppress the immune system. Yes and the cost of all are very high.

I have MS, and recently switched from Copaxone shots (on for 5 1/2 yrs) to Tysabri infusions (I've had three) due to slow decline. I have a flu shot every fall and was wondering if I should have one this year since I'm on a new med.

Hi there, I am in the process of switching to Tecfidera after a year of Rebif, my first DMD. I switched 7 weeks ago but started having some nasty gastro issues during week 5. I am back to the starter dose of Tecfidera and will work back up to the full dose much slower this time.

I've been on tysabri for over a year and developed a bad itchy rash the past 3 months. Thanks so much for your input and I will check back with her posting. Good luck to you too!

I started rebif Nov/12 since being on this medication I have not felt normal,it is like the flare up that will not go away. Prior to Oct.

The injections only work 33% if started at the beginning stages of Relapsing Remitting MS. There is Tysabri an infusion and their are drug trials for oral medications. Sometimes they can even use chemo but it is rough stuff. Unfortunately to date these are the only proven treatments. Some people go to other countries to get stem cells. The problem is stem cells can't repair damage they can only in some cases slow future damage but usually only for awhile.

Hi, Cammie, I failed Rebif after 2 back-to-back flairs. It also gave me hives. I started Tysabri in February, and had my 2nd infusion 2 weeks ago. I haven't noticed a big difference, yet. I have quite a bit of fallout from my last flair, namely, my inability to play my guitar for more than about 20 minutes. I've had to quit performing for the time being. I have a crazy strong immune system, and therefore not at huge risk for PML.

I have failed rebif and my liver didnt tolerate tysabri after 10 infusions. I really didnt like the side effect profile from tecfidera and was hoping this was gonna get approved.

Hi Kat - I will get my 11th infusion in about 10 days. I have had no issues of any kind in conjunction with Tysabri. From the follow up MRI's I've had Tysabri seems to be doing the trick. No new lesions or relapses since I started. You will be tested for the JC virus prior to starting.

Tysabri vs rebif

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