tysabri vs gilenya

It involves only one patient so far, and that patient is still alive. Despite ahving not used tysabri, they had used an interferon just before Gilenya, and steroids both before and during the Gilenya treatme t. Worth keeping an eye on this story, for sure.

Novartis (the maker of Gilenya) at this point is attributing the PML to the prior Tysabri usage, but they acknowlege "that the contribution of Gilenya to this case can not be excluded." I figured I'd post this just as a heads up ... not trying to freak anyone out, just something to be aware of and keep an eye on. It will be interesting to see if this will be an isolated incident, or if there will be more cases to follow.

S in Boston just to see where he would land on the Gilenya vs Tysabri question. Out of curiosity more than anything. I asked my neuro, isn't the point to prevent me from getting that bad to begin with? He agreed but led me through a methodical decision process re: staying on Copaxone, switching to an oral, and Tysabri. The whole risk vs reward thing.

If you choose to go off of Tysabri, there is going to be another washout period. The recommended length for Tysabri to gilenya, is about 4 months. During that time, the recommended protocol is to trreat the patient with routine rounds of steroids until the gilenya can be started. I asked this question recently and the washout to go to the other DMDs can be about 30 days, just not the jump to Gilenya. The Incidence of PML is small, but that is no comfort to those people who contraact it.

t do a lengthy washout period after stopping tysabri and I understand that patient had also been on tysabri for a longer period of time. How will they ever untangle is it was the Gilenya, the Tysabri or both that opened the door for PML to enter? Argh! Why aren't answers these days just clearly marked? I hate having all these unanswered questions about therapy that is so critical.

(I saw her about 2 weeks ago, and she wanted to switch me from Copaxone to either Tysabri or Gilenya. There needed and still needs to get lots of tests. They have very stringent rules who goes on these meds. She told me I was negative for the JC virus and would like to know my thoughts about this. Would I be willing to try Tysabri? She knows I was overloaded with info at the last visit and wants to go over all this.

I recall that TLC_31 has said that he had to discontinue Gilenya due to cardiac side effects. I can't recall anyone else here (of the regulars) who has tried it. Try searching the forum using Gilenya as keyword, to read past posts about it. If you're on Facebook, search for the private group Gilenya. I joined it recently, and the Tysabri group too, as I'm facing the same decision you are, Candy.

I don’t know anything about gabapentin, other than that it is not a disease-modifying drug interchangable with Gilenya, Tysabri, Copaxone, Avonex, Rebif, and Betaseron. If you need to switch from Copaxone and you are uncomfortable with the low risks of Gilenya and Tysabri, the others have a good safety profile and side effects that usually can be mitigated.

Took my first dose of gilenya today heart rate drop to 50 so had to stay an extra hour but home now. Hoping this works since I failed rebif, tysabri, tecfidera we shall see what happens.

Janine, Wishing you well with the new oral med. Like Daisy girl, I was given the options for Tysabri and Gilenya. I will be doing Tysabri, for 1 year. If not doing what it "should" be doing, I will then most likely start Gilenya.

Hi, His doc suggested Rebif or gilenya,. We are a little afriad of the gilenya because it is so new. You have to see so many specialist before you go on it. Do you know anyone on gilenya. Thanks for your input.

she things, but likes to know more info about the meds. She is more comfortable with Tysabri then Gilenya, and hasn't put anyone on Gilenya yet. The MS center is having a study with about 250 patients that will be prescribed Gilenya. She has "only" put about 30 people on Tysabri at this point, but believes that will increase once she is more confident with the meds. She has been an MS neuro for quite a long time, and I completely trust her, and feel I have gotten enough info.

Over the last 12 years he has been on Avonex, Betaseron, Copaxone drugs. Now he is completing the 2 year mark of using Tysabri. Dr Appointment in 2 weeks assume he will stop infusions. I wonder what is next???? How are others doing after all these treatment and now what do they take???

I changed to Gilenya. I had been on Betaseron for 1 year. During that year, I had the relapses that required steroid infusions. My Dr. thought that this was too many. I got off the Betaseron at the 1 year mark to try to conceive my 3rd child. After she was born, I started taking Gilenya. I have two different Dr.'s that I see for my MS. I like always haveing a second opinion. they both agreed that I shcould change.

http://nationalmssociety.org/news/news-detail/index.aspx?nid=3871 has their release here. The point on my posting this information is to remind everyone that even though a pill may be simpler to take, it is still a drug with potential ill effects. If the injectibles didn't work for me, I would certainly be open to trying Tysabri or Gilenya. Sirtting back and doing nothing out of concern for the side effects is not an option for me.

The other NEW drug choice for him would be Gilenya. There may be a Washout period between Tysabri and Gilenya before he begins this new drug. A recent study showed that people who go off Tysabri will most probably experience a serious relapse in their MS.

Spoke to my MS nurse today and she seemed to favour Gilenya over Aubagio (more effective) and Tysabri (potentially less risky). Will be speaking about all the options with neuro, hopefully soon. So far Gilenya is the only oral covered by the MS Drug Program in Alberta. The others are awaiting approval and expected to go through. For me is not really an issue as my employer group plan covers all the DMDs.

I was offered Gilenya when I had problems with Tysabri (which turned out to be something other than Tysabri that caused it) and after reading the cardiac warnings and other side effects, chose not to take it. Tysabri has a wonderful financial support program. They fully donated my first 4 months of Tysabri until I could get an insurance program in place. Tysabri is considered an "outpatient" procedure and under my insurance, is paid for now at 100%.

It is being recommended that I switch from Copaxone (or any shot) to Tysabri, Tecfidera or Gilenya. What are you guys using?

If your MS is more aggressive, then you may be more inclined to consider Gilenya, Tecfidera, Aubagio, or Tysabri. All of the DMDs are discussed from a neutral perspective at the link below: http://www.nationalmssociety.org/Treating-MS/Medications Choose a medicine that you can adhere to the dosing schedule. If you would forget to take pills, for example, you need to be on an injectible. Consider the common side effects and which ones you can most readily live with.

Tysabri vs gilenya

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