tysabri virus

I wonder if you can still get treatment with Tysabri if you test positive for the JC Virus. My sister has been on Tysabri for three-four years now and is positive for the JC Virus. She's got nothing but great things to say about the drug . . .

I got the official JC virus results, and I am JC positive. We are still staying with the Tysabri at this point, since we feel it is helping me.

This was an interesting report - it was also reported via MedLine in perhaps an easier format to understand ---- http://www.nlm.nih.gov/medlineplus/news/fullstory_125250.

There is an alogirthm for the chances of contracting PML while on tysabri. I believe it is on the tysabri website among other places. I will see if I can find it for you and report back.

I had my 5th Tysabri improvement last Sunday. Since then I have noticed a major improvement in the way my legs feel and work. I mean a major improvement. My legs have not felt this good in a very long time. I have also been exercising regularly for the last month and have lost a bunch of weight. I'm trying to determine to what I can attribute the improvement. Is it the Ty infusion? The exercise? the weight loss? I'm kinda hoping it's the Tysabri.

HOWEVER if you continue to test negative for the JC Virus there is no reason you should have to stop tysabri if it is working for you. In fact, stopping Tysabri is shown to cause serious relapses and is not something fun to go through. I would talke to a different doctor about tysabri and get off the holiday idea. Of course if you test positive for the JC virus, that is a different story entirely. good luck in working this through with your medical provider.

i have read up on tysabri and i dont like when i have read,they drew blood today to check for the jc virus.

Over the last 12 years he has been on all the ABC drugs. Now he is completing the 2 year mark of using Tysabri. Dr Appointment in 2 weeks assume he will stop infusions. I wonder what is next???? How are others doing after all these treatment and now what do they take???

In the time I have been taking Tysabri, they have obtained much more data, as more and more people began taking Tysabri and staying on it longer. The JC virus test has been very helpful, allowing people who are negative to go on Tysabri with much less worry of PML, as well as giving people who test positive a better idea of the risks and allowing them to make more informed choices and decisions. At this time, they have identified 3 main risk factors for PML while on Tysabri: 1.

The Risk of PML is greatest in the setting of a positive J-lymphocytesC virus, greater than 24 months of Tysabri, and concurrent use of other DMD's or steroids. Those are old recommendations, and new info will change them in the (near?) future. PML is caused by the J-C Virus. A little more than half of all people have been infected with the JC virus. It generally lives asymptomatically in the brain unless something has occurred to cause the immunity of the brain to be compromised.

I've been on Tysabri since 2012 and tested + before I started. Some months I feel better, some I don't.

I'm just curious - what kind of study are you involved in? I'm on Tysabri too... just had blood drawn for the JC virus antibody study. Is that the one you are talking about?

Hello, I was wondering if I took tysabri with having MS also RSD because with having the rsd it does weakend my immune system, I don't believe this would be a very wise decision do you?

He asked me whether I was interested in being in the Tysabri study. I am only 37 and have only had one relapse. I know I will be deciding on a treatment and not sure what direction to go. This neuro is big in research and he spent a lot of time talking with me about MS. He mentioned a JC Virus and took my blood to look for it. If I don't, I would be a good candidate for Tysabri. It has 67% reduction in relapses but also risks getting PML.

Does anybody have any experience with Tysabri? I just tested positive for the JC virus and my doc still wants to put me on it for 6 months. He says that the risk of getting the brain infection is very low since I will only be on it for a short period of time. My other option is to go on Gilenya, I am not sure what to do.

My new neuro suggested Tysabri based on increased lesions on Interferon (Rebif). Any persons out there on Tysabri that could share their experience?

My Neurologist is not a big fan however. She will suggest almost anything before discussing Tysabri, but now with the JC virus test, she seems to be warming up to the drug. I am going to put it off for a while and think about it. Luckily I haven't had any immuno-suppressant treatments so getting a negative JC test would certainly make me a good candidate for Tysabri. I just want to give IVIG a bit more time.

Diagnosed 2/14/13 with PPMS. Neurologist wanted me on Copaxone. Finally started it on 03/12/13. Received a letter from neurologist on Friday(02-15-13) that he would prefer me to be on Tysabri. I am negative for the JV virus so it is something that is possible. Just don't understand the quick change. Any thoughts?

There are several of us here on Tysabri - I made the switch after about three years on copaxone. It takes a day a month to stop and have the infusion, and then I go on ny way for another 4 weeks. So far, even though some of my symptoms continue to progress. my MRIs are stable with nothing new that would excite me or my neuro. I am also JC negative, hitting my two year mark, and plan to stay on it until I have to stop.

I was on beta seron for months.. Now starting tysabri.. No I don't carry jc virus. Anyone have input on this? My lesions are in brain and cervical spine is a mess with lesions. Arms n hands are awful. Have had the hugs as well. And the almighty "zapper", the elect current that runs through torso and hits you in the pelvic area. This disease is quite difficult to keep up with. Here then there then another area...

Hi Kat - I will get my 11th infusion in about 10 days. I have had no issues of any kind in conjunction with Tysabri. From the follow up MRI's I've had Tysabri seems to be doing the trick. No new lesions or relapses since I started. You will be tested for the JC virus prior to starting.

Some people with MS have a dormant Virus in them called JC Virus. Tysabri will trigger that Virus, the Virus lays dormant in the Brain. Until they approve the PRC Blood test for that Virus, there is only a slight way to detect it, and that is with a Brain and CSpine MRI. Therefore, Tysabri is quite risky. Copaxone, on the other hand is a much "cleaner" treatment, less risky and easier on your system, with about the same amount of side effects as MS itself. Copaxone is safer.

She told me I was negative for the JC virus and would like to know my thoughts about this. Would I be willing to try Tysabri? She knows I was overloaded with info at the last visit and wants to go over all this. She said she has done lots of "thinking" about what med would be most effective for me. I appreciate her doing her job so well. I have total trust in her, but am really nervous about this med.

I do not have typical ms, but a variant that is still clinically not diagnosed. I have a great neuro @ Stanford & he is recommending I start on Tysabri ASAP. I read up about the JC virus, and regardless plan to begin treatment next week. I don't know anyone with ms or ms variants so I want to know more about Tysabri from people who are on it or have used it. What is your experience? Pros/cons? I have read about side effects but I want to hear your thoughts & how it made you feel.

I am one of the older posters, and I am still on Tysabri. I just had #32. I had the JC virus test but still haven't gotten my results. Overall, my neuro and I both feel that Tysabri has helped slow down the parade of symptoms I was having, and that I'd be alot worse off right now if I wasn't on it. Feel free to PM me if you have any questions. ....

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