tysabri update 2008

My MS doc always gives a small dose of Solumedrol, which is much larger than a usual prednisone dose, to his new Tysabri patients. They get the IVSM in the first hour. Then they get the Tysabri in the next hour. His experience says that the mini-dose of IVSM helps the Tysabri get to work faster by cutting any inflammation in our system. He does that for the first three Tysabri doses when just beginning this therapy. I hope you are less itchy today and can reach your doctor in the morning.

There have since been cases of PML as well as some deaths in patients who were taking only Tysabri at the time. When I started Tysabri in 2008, the estimated risk of PML was 1 in 1000. They knew being JC positive was a risk factor, but there was no test for it at the time. Most estimates I've seen are that approx. 50-60% of ALL people carry the JC virus, as it is actually very common.

They found out the reason people contracted PML was because they were taking Avonex/and the other MS medications with Tysabri. I think the Tysabri has given me a second chance at helping slow my disease progress, but with out it I would be on no MS medications to slow the disease. I did alot of research before I decided to start the medication and the one resource that helped me make my decision was reading the Tysabri diaries on line. www.msrc.co.uk/index.cfm?

Hope everyone is well. I just wanted to give an update. I had my first Tysabri infusion this morning and I experienced no side effects so far at all. Over the last 2 months I have had some improvment. I still have all my symptoms but they're less intense. So here's hoping for the best. Hoping this medication works at seriously slowing this beast way down. How are things with everyone? I truly hope everyone has been well or well as can be expected.

Thanks for the update! Good to know the only side effect was a one nighter. Looking forward to hearing more as your journey continues.

Talked with Tysabri caseworker this morning and gleamed some more info as follows; You call them or Tysabri in my case and tell them you are interested, they then send a referral notice to your doctor and in about 2 weeks someone calks you from undetermined #, I asked to be notified or gave them leave a msg as u don't answer for numbers I don't know, and they will discuss your insurance info then, etc.

s financial asistance program to update my status and make sure that the Tysabri AND the administration fee (probably your $350) are covered by Biogen. Please call them back and see if you qualify for this generous offer.

• Although the absolute risk for PML in patients treated with Tysabri cannot be precisely determined, the U.S. FDA and the company have released data suggesting that the risk increases with increasing time on therapy. • The company changed the label of Tysabri to indicate that the risk of PML is increased in patients who have been treated with an immunosuppressant (such as mitoxantrone, and less commonly, azathioprine and methotrexate) prior to receiving Tysabri.

I am conducting my own, personal study on the benefits of Tysabri in conjunction with SPMS.

I have failed rebif and my liver didnt tolerate tysabri after 10 infusions. I really didnt like the side effect profile from tecfidera and was hoping this was gonna get approved.

I had been on Tysabri for 22 month's and just recently stopped. I was wondering if any new info. is out there on the drug Rituxan for MS? I have SPMS with RRMS. I was in a study 3 yrs. ago at UCSF and did really well on Rituxan. However, Rituxan is not an approved drug for MS and at that time my insurance would not cover it so I had to discontinue taking it. Or should I just take a break for awhile and not take any ms med"s?

He is comparing to a May 2009 done there but by a different reader. Oddly the last one he read on mine was May 2008. It is the May 2008 report where he specifies various dimensions of lesions. He describes them now as larger yet writes "unchanged." I know radios have a language all their own and their use of words is not the same as street English! The prescription just said MS.

09 and I have since switched to Tysabri. With tysabri, all of my symptoms, (tingling, numbness, and pain) are all but gone. For me, Tysabri was more effective then Copaxone, but if you have MS and are thinking of switching, Tysabri is a very dangerous drug, inform yourself before making the decision.

Tysabri update 2008

Common Questions and Answers about Tysabri update 2008

tysabri