Tysabri study

Common Questions and Answers about Tysabri study

tysabri

233622 tn?1279334905 I'm just curious - what kind of study are you involved in? I'm on Tysabri too... just had blood drawn for the JC virus antibody study. Is that the one you are talking about?
1045086 tn?1332126422 Attention all Buckeyes (PwMS living in Ohio): This study is recruiting 24 people diagnosed with RRMS to participate in stem cell therapy research. Testing and procedure will be conducted through the Cleveland Clinic Mellon Center http://www.nationalmssociety.org/news/news-detail/index.aspx?nid=2525 ---------------------------------------------------------- This one is a clinical study being conducted by Biogen to evaluate the effectiveness of Tysabri in people with SPMS.
572651 tn?1530999357 I've been tested twice in the last year, and they were both negative. Since you can acquire JCV at any time, I opt to have my status tested once a year since I'm on Tysabri. There is also a Tysabri antibody titre available, now. I plan on doing that once a year, too, although development of Tysabri antibodies is relatively rare.
572651 tn?1530999357 Speaking of Tysabri, the first two months I had a ton of energy after my Tysabri infusions, now that I have had 4, that has gone away, sigh. Will hope they return! Of course it is getting warmer and I don't "do warm" very well.
1896537 tn?1381900009 Hello all, It just suddenly occurred to me that I hadn't logged in here for ages so I thought I'd see how everybody is getting on. Also, for those of you who knew I was not on a treatment for a long time, I have started Tysabri! My second infusion is on Thursday & I'm daring to feel very positive. I was very surprised by the first infusion.
1637739 tn?1371688706 He asked me whether I was interested in being in the Tysabri study. I am only 37 and have only had one relapse. I know I will be deciding on a treatment and not sure what direction to go. This neuro is big in research and he spent a lot of time talking with me about MS. He mentioned a JC Virus and took my blood to look for it. If I don't, I would be a good candidate for Tysabri. It has 67% reduction in relapses but also risks getting PML.
572651 tn?1530999357 I am conducting my own, personal study on the benefits of Tysabri in conjunction with SPMS.
198419 tn?1360242356 As of March 2008, more than 26,000 patients were on Tysabri® worldwide. Since the re-launch of Tysabri in July 2006, no new cases of progressive multifocal leukoencephalopathy (PML) have been reported. PML is an often-fatal viral infection of the brain. Data from the PLEX study suggest that plasma exchange may be an effective procedure for accelerating the removal of Tysabri from the blood if PML infection is suspected.
Avatar f tn Of course you're a lab study - unfortunately a Tysabri TOUCH study isn't going to give you the kind of neurological care that you're needing. And it sounds like the people you've been seeing don't know much about MS, which is unfortunate. That the study excludes spine MRIs is also unfortunate - you'd think that they would include that information. But I can understand why.
1831849 tn?1383228392 s as part of JCV/PML detection protocol. I am having a blood test, brain MRI and an LP every 6 months as part of my Tysabri treatment. This article from the Journal of Neurology discusses this protocol. http://www.msrcny.org/sites/default/files/articles/JCVpaper.
Avatar n tn Okay, I've had MS for 13 years. I was just taken off Tysabri in July, I was on that for almost 5 years. I now have to go on Gylena in January, but before I start the new drug...I have to do 6 months of iv steroids. 3 days every month with NO taper! I have just finished my second round...and I'm ready to through in the towel. The side affects of the steroids are at this point almost not worth doing. They are trying to prevent a relapse since I am not on any MS therapy.
1831849 tn?1383228392 Something new from the man who developed Tysabri. This talks about repairing/reducing inflammation. http://www.businessweek.
198419 tn?1360242356 HI Rita, My friend on Tysabri that you spoke to always got frequent UTI's while on Tysabri, She went off the Tysabri six weeks ago since she was getting alot of new lesions on her spine and wanted to try LDN. Now that she is off the Tysabri, she is having pain for the first time with MS. She is not getting very good effects from the LDN and may end up back on Tysabri. I'll catch up with you later!!
Avatar f tn Most know my unhappy experiences with Tysabri recently but DH drug me home from the ER early this morning. Had been nauseous and upchucking since Monday after my August Ty infusion 10 days ago. Nice doc, ran tons of labs (only WBC was elevated) and x-rays and wonderful meds and hydration fluids. He and I both feel was Tysabri side effect.........now the interesting part is that I seriously burned my esophagus and now have days of liquids and meds while it heals.
1950519 tn?1324518193 There may be a Washout period between Tysabri and Gilenya before he begins this new drug. A recent study showed that people who go off Tysabri will most probably experience a serious relapse in their MS.
Avatar f tn When my neurologist suggested going back on Tysabri, I told her I wanted to wait for the results of the study before making a decision. Two weeks later I found out my results; I tested positive. My neurologist was quite upset about the findings and she said there was no way she would put me back on the medication now. If they tested you for the JC virus and it came back negative, you’ll probably be okay taking the infusion.
572651 tn?1530999357 You might find this of interest- I have always wondered why we startt out wit hthe weakest drugs to treat our MS instead of going at it as agressively as possible - Biogen Idec and Elan Submit Applications for First-Line Use of TYSABRI in anti-JCV Antibody Negative Patients with MS http://tinyurl.
Avatar n tn To be honest right now my doctor is being a butt and rude for the first time ever. He can not even give me this Tysabri. So I would not even see him if I did take it.
560501 tn?1383612740 He demands I take tysabri which I am uncomfortable with as feel its just too dangerous and not.enough study on it. He confused me as my ep.tells me to.try to.exercise as I.can because its good for.heart and strengthens legs. Neuro says if.I exercise I will destroy what's left of my autonomic.system and have serious.cardiovascular problems. I talked to my primary Dr as ep.is on cruise. He.is as confused as I am. By the way I tilt.to.the right.,lol we r twins.
147426 tn?1317265632 The Risk of PML is greatest in the setting of a positive J-lymphocytesC virus, greater than 24 months of Tysabri, and concurrent use of other DMD's or steroids. Those are old recommendations, and new info will change them in the (near?) future. PML is caused by the J-C Virus. A little more than half of all people have been infected with the JC virus. It generally lives asymptomatically in the brain unless something has occurred to cause the immunity of the brain to be compromised.