tysabri rebound effect

I will start tecfidera in 3 months I hope I dont have the rebound effect I have heard about after stopping tysabri. Tysabri has really changed the way I feel was using a walker now nothing and I do Zumba too. I hope I stay like this but having doubts. anyone using tecfidera? How was your experience.?

I have also heard of the rebound effect after coming of tysabri. So far ive noticed my fatigue is worse and my balance is off again but not like it was. Before tysabri I had a cane and walker now I use nothing and would like to keep it that way. I started doinf volunteer work for hospice and love it. I would hate to go back to what I was before tysabri. I am seeing ms specialist dec 31st to see what my options are for dmd. I wont go back to shots and not happy with side effect profile from tec.

m hanging in there. I get sick alot these days. The Tysabri seems to have more and more of an effect on my immune system. Having skin issues due to it as well. Also having alot of stomach issues the past few months - the GI guy feels that the MS is causing my stomach to empty slower, and thus causing alot of other problems. I'm in the process of yet more tests, lol. I got approved for SS disability just before Christmas - I cried for 3 days ...

Now that i am off of Tysabri for over a month, am getting more pesky symptoms. My foot drag is worse, I do more drunk walks, drop more things, use wrong words more often and last night was up with extreme dizziness and nausea and woke up this morning with a new case of ON. Interestingly enough, they are talking about putting me back on Tysabri, I had no antibodies to it (tests are back) and still am having the GI problems. The current theory is that MS is causing the GI problems.

I have decided to stop taking the aspirin, which I haven’t taken in about a week anyways. This “rebound effect” that can result in clotting due to suddenly stopping aspirin has got me a little worried. Is this a legitimate concern or am I worrying for no reason? I understand the negative effects of stopping aspirin are mostly in the 4 weeks or so after stopping due to platelets becoming “more sticky”. How long after stopping aspirin does the blood “normalize”?

Was doing really well on it, from Jan 2010 until the summer when I lost my voice for 3 months. Tysabri was D/C then per Neuro. In case that was a side effect. I went back on Tysabri in Dec. My voice is still an issue. Neuro doesn't know still if side effect, and is leaving it up to me if I want to stay on. She would like me to stay on it, as there is no other alternative for me at the moment.

I am having a side effect from , I think, from my 1st Tysabri infusion 3 days ago. About 15 minutes into the infusion, I became extremely nauseous. It got really bad, and I needed a bucket. Got better, and has been coming in waves ever since. I spoke with NP at neuros office yesterday. Called in an anti-nausea medication. That is giving me a bad bad headache. The NP told me she had never heard of nausea as a side effect. She thinks it is coincidental. Has anyone here experienced that?

My very excellent neurologist told me that Frova and Amerge are the ONLY triptans that do not cause the rebound effect as they have more of a half-life. The other triptans can then be used once a week. NO over the counter pain meds like Advil- those cause rebounds too. My neuro gave me Ultram, which is a better choice for chronic and frequent headaches.

) Think I am sticking with Tysabri for now, seeing neuro as well tomorrow and I know I will get a good report. Having a great summer with my boys... Just a quick update. I haven't been on the boards for some time, not too much extra time right now. I imagine September I will be back more often. (It is strange, i rarely think of MS anymore. I would love for that to stay.0 The only thing that has been increasing is Migraines.

Know others have worse problems, but I'd just love a vacation without Tysabri side effects. I diligently took my Prilosec for the 5 days, and wouldn't you know, on the 6th day, I was back in ER that night, hooked up to IV and fluids. They had to give me a bolus bag before they could draw blood for the labs, guess I was dehydrated. I love it when they make regular rounds with WARMED blankets!

It's 99% official - they are taking me of Tysabri - my allergic reaction (GI difficulties) was getting worse. My neuro drew blood for an antibodies test - he thinks my body has developed antibodies to fight Tysabri, and if that be the case, I am 100% off of it. So am taking a "holiday", knowing the rebound I am facing, to recover. We will make a final decision when the blood test come back.

I also had a headache and joint pain right after the infusion. Will Tysabri help with tiredness after a few infusions?

Vasoconstrictors that are in eye drops like Visine, Cleareyes, etc cause rebound effect. They are not safe for long term use. I've used Euphrasia (eyebright) before and it makes my eyes feel so fresh and also gets rid of redness. I've been doing research on this herb and I've read that it shrinks tissue. I want to get a doctor's thought on the long term use of this herb. This herb helps with my eye allergies and that is why I want to use it.

Just curios why would anyone use a medication with this possible side effect? I was diagnosed with PPMS in 2008... I am treated at Beth Israel Hospital in Boston, MA by a top MS specialist.

From everyone I talked to, there is a feel good/better effect with the Tysabri that lasts about 3 weeks. About that 4th week you will know that you are ready for the next one. It may be wishful thinking for this first infusion, because I hear it is usually three or so before the effects really kick in. But hey, if you are feeling better we can't complain, right?

I have failed rebif and my liver didnt tolerate tysabri after 10 infusions. I really didnt like the side effect profile from tecfidera and was hoping this was gonna get approved.

Nice doc, ran tons of labs (only WBC was elevated) and x-rays and wonderful meds and hydration fluids. He and I both feel was Tysabri side effect.........now the interesting part is that I seriously burned my esophagus and now have days of liquids and meds while it heals. So anyone on Ty, please read those side effects and take them seriously, they can get you into trouble before you know it. Not sure what am going to use for DMD now, thinking of a nice rest period of NOTHING.

My first DMD drug was Tysabri and I have been on it almost 2 yrs, and was JC+ from the start. Tysabri is very good at lowering relapses, but of course, does not correct anything already there. You may continue to have relapses or attacks, it is not 100%, but does a good job. It is not usually a first drug, as you have been told, but your doctor had a good reason or he would not have put you on it As Kyle said, let your doctor know…….

Took my first dose of gilenya today heart rate drop to 50 so had to stay an extra hour but home now. Hoping this works since I failed rebif, tysabri, tecfidera we shall see what happens.

Which (CRAB/Tysabri) medication do think has the least side affects? Please vote because this poll is for an individual trying to make a serious decision, and the doctor told this person to choose their own treatment.

I was recently told that even a single dose of OTC or pain killers can cause a rebound headache. I also have chronic daily headaches as well as a few migraines each week. Can the ER cocktail of Benadryl, Toradol, Zofran, Reglan, ativan ,and decadron potentially cause a rebound effect. There's some weeks, I'm in the ER 2-3 times per week . Some months, I don't go at all. At home, Ido not take anything except amlodapine and valium twice a day.

Tysabri rebound effect

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