Tysabri ms research

Common Questions and Answers about Tysabri ms research

tysabri

198419 tn?1360242356 As of March 2008, more than 26,000 patients were on Tysabri® worldwide. Since the re-launch of Tysabri in July 2006, no new cases of progressive multifocal leukoencephalopathy (PML) have been reported. PML is an often-fatal viral infection of the brain. Data from the PLEX study suggest that plasma exchange may be an effective procedure for accelerating the removal of Tysabri from the blood if PML infection is suspected.
1831849 tn?1383228392 The research side of my MS Practice has identified a CSF biomarker for disease activity. The research is featured on the cover of this month's Multiple Sclerosis Journal. http://tischms.org/news/tisch-ms-breakthrough-biomarker-research-featured-cover-article-october-2013-issue-multiple I'm a beneficiary of this discovery. I had been on Tysabri for 20 months. At 18 Months I converted to JCV +, and we discussed switching from Tysabri to Tecfidera.
Avatar m tn I just heard a local neuro talk about using doses of steroids to control MS problems during the washout period (usually about 3 months) between tysabri and gilenya. Your final statement to Sarah is so wrong in so many ways - the doctor who says you don't treat a progressive disease needs to lose the medical license and get into a different line of work. There is definitely treatment for all of us...
1475492 tn?1332884167 Someone said that Jose who died from PML were taking more than one MS medication. Is that more than one DMD or treatment for symptoms?
216354 tn?1262871346 However, she was also told that if she were to stop tysabri she was pretty much guaranteed to have an attack of the MS. She has an agressive form of MS and other medications don't seem to work. We haven't seen much improvement with tysabri, but at least she hasn't had anymore attacks while on it. Can anyone shed more light on this for me? I was hoping to gather more information on this if anyone has it. Please let me know! Thanks!
Avatar f tn My doctor thinks tysabri would be a great next choice. What confuses me is that all the research I have done seems to insinuate that tysabri is a good choice when nothing else works. I am in great shape and live with little to no daily symptoms. My main Symptom is my left leg dragging after about 20 min of walking for exercise and I haven't been able to run for ten yrs now. Please give me your insight as to why you think I should or should not switch to Tysabri. Thank you!
Avatar f tn They found out the reason people contracted PML was because they were taking Avonex/and the other MS medications with Tysabri. I think the Tysabri has given me a second chance at helping slow my disease progress, but with out it I would be on no MS medications to slow the disease. I did alot of research before I decided to start the medication and the one resource that helped me make my decision was reading the Tysabri diaries on line. www.msrc.co.uk/index.cfm?
5681139 tn?1372268736 He reiterated that point yesterday. There are pluses and minuses to all MS meds. For me a big Tysabri plus is that I only have to deal with it once every 4 weeks. The thought of daily or weekly self injections was not all that appealing to me. Right before I saw my neuro yesterday I saw my naturopathic doc. Her office is two doors down from his, in the same MS practice. They work together and each is aware of what is being discussed with the other.
252144 tn?1227422620 I decided to research Tysabri and it sounded scary, but I was willing to try anything. That is when I asked my Dr. about Tysabri. This is a monthly infusion that last 1 hour. My first infusion made my heartbeat a little fast, but I was nervous. I went straight home after the infusion because I expected to be sick. I wasn't! As the day went on I started to feel like I had more energy, but I was afraid if I got up and started doing things I might end up sick so, I just rested that day.
Avatar m tn The injections only work 33% if started at the beginning stages of Relapsing Remitting MS. There is Tysabri an infusion and their are drug trials for oral medications. Sometimes they can even use chemo but it is rough stuff. Unfortunately to date these are the only proven treatments. Some people go to other countries to get stem cells. The problem is stem cells can't repair damage they can only in some cases slow future damage but usually only for awhile.
572651 tn?1530999357 You might find this of interest- I have always wondered why we startt out wit hthe weakest drugs to treat our MS instead of going at it as agressively as possible - Biogen Idec and Elan Submit Applications for First-Line Use of TYSABRI in anti-JCV Antibody Negative Patients with MS http://tinyurl.
Avatar f tn Hi. I'm new to MS and Tysabri. I was just diagnosed in July of this year. I basically had no symptoms. Maybe a little fatigue and dizziness but it was always "explainable". I wouldn't even have gone to the doctor then if it weren't for numbness/tingling in my hands. I work on a computer all day so it was very annoying and I broke down and went. And after a few MRIs and other tests this is where I am.
Avatar f tn I would hate to go back to what I was before tysabri. I am seeing ms specialist dec 31st to see what my options are for dmd. I wont go back to shots and not happy with side effect profile from tec. I was hoping lemtrada would been approved by now as I would try that.
572651 tn?1530999357 Beth, here's what I think I know: PML - is a hard-core demyelinating disease that's somewhat similar to MS but more like MS on major steroids - and most of the time it's fatal, since there's no cure. It's caused by the JC Virus. JC Virus - is already present in a lot of people - but once it's activated (or maybe rather, re-activated), it can cause PML. If your immune system is REALLY low, then this could happen (ie from the use of chemotherapies).
Avatar f tn I saw my neuro on Friday and in the course of a fairly long appointment and discussion, I asked a lot of questions. One in particular had to do with oral meds, which we've been told for years are right around the corner. He says yes, they'll definitely be available very soon, but prescribing them will be difficult because of their side effects. Only select patients will get them. I asked if this included those who couldn't tolerate or just didn't do the injections.
1831849 tn?1383228392 Something new from the man who developed Tysabri. This talks about repairing/reducing inflammation. http://www.businessweek.
Avatar f tn Using Tysabri as a first DMD has more to do with the stage of your MS than your age. My first DMD was Tysabri. It was chosen because by the time I was dx'd I'd moved from RRMS to SPMS. There are no DMDs apporved to treat SPMS. This means that the firstline meds Copaxone, Rebif, Avonex and Betaseron (CRAB) are not generally effective against SPMS. The same is not true for Tysabri. It is considered to be more potent than the CRABs and is used in SPMS cases.
1475492 tn?1332884167 Hi SS - Congrats on your move to Portlandia. Even bigger congrats on getting back in your running shoes! Keeping our bodies as strong as we can is really important. As to Tysabri's healing powers I'm not so sure. I am sure that it is effective at dramatically slowing the progress of MS. I'v had 18 infusions and Tysabri is the only DMD I've used. Since starting Tysabri I've seen no appreciable worsening of my MS. If I can stay where I am now I'll be very happy.
Avatar f tn First diagnosed with MS in 2013 when I went blind in my right eye, I was put on steroids and than later Copaxone 5 days a week than 3 days a week which didn't last long either because my doctor found legions on my spine and told me he thought tysabri would be the best option and I needed to make my decision quick. I did do my research on tysabri but I don't think I want to be on this for the rest of my life.
Avatar f tn No daily injections (a constant reminder that I have MS and I have to treat it), the reminants of the syringe in my house, in my fridge, sharps bin in my press. Filling the prescription at the pharmacy. These were all things I wanted to banish as a mechanism to think about having MS a little less.
1115136 tn?1258778476 Before Tysabri, she was taking Rebif, and her MRI was showing advance in lesions. I think Tysabri has helped to slow down her MS, and if you ask my sister whether or not Tysabri has made a difference, she would most certainly say it had. For those of us with MS that have a more aggressive disease course, it's nice to still have an option available for us.
1831849 tn?1383228392 This test is just another level of monitoring. The research I read says that in patients being treated with Tysabri, these bio-markers, and thus DA, should be at very low levels. In my case the elevated levels indicate that the Tysabri was not as effective as it was supposed to be. My levels were not elevated in previous LP so the Tysabri was likely working for a while. Now that we know it's not we move on to Plan B.