I'm sorry you're feeling so cruddy. Tysabri
has done well for me in preventing any major relapses
, but like you, I'm always having pseudo relapses, and just basically, slowly declining. I don't know that any DMD has a perfect record for stopping MS disability cold. The research has come up with figures in the 30-50% range for slowing disability (30% for Copaxone, up to 50% for Tysabri).
Hopefully, as Summer winds down, your pseudo flares will settle down, too. Hang in there...