Tysabri melanoma

Common Questions and Answers about Tysabri melanoma

tysabri

294425 tn?1288528395 Hey Guys, Just wanted to give you all a heads up, in the interest of us all being informed patients... :) I saw this article this morning, and here's the crux of it: "New Case of PML Confirmed in U.S. A new case of PML, or progressive multifocal leukoencephalopathy, has been confirmed in the U.S., in a patient receiving Tysabri for the treatment of MS. After 14 treatments, the patient reported a change in health status, and the patient’s physician began testing for PML.
198419 tn?1360242356 As of March 2008, more than 26,000 patients were on Tysabri® worldwide. Since the re-launch of Tysabri in July 2006, no new cases of progressive multifocal leukoencephalopathy (PML) have been reported. PML is an often-fatal viral infection of the brain. Data from the PLEX study suggest that plasma exchange may be an effective procedure for accelerating the removal of Tysabri from the blood if PML infection is suspected.
Avatar n tn She is fair skinned, her paternal uncle died of melanoma when he was only 40 and her brother has melanoma. Does this increase her risk of developing melanoma?
Avatar n tn Hi. Where was your melanoma located? Was it near your nose? I checked the official prescribing information for Veramyst (fluticasone nasal spray) and it does not specifically state that this drug is contraindicated for those with melanoma or any other cancer. However, for those with recent nasal surgery, this drug should be avoided as it delays wound healing and increases the risk of fungal (Candida) infection.
Avatar f tn They found out the reason people contracted PML was because they were taking Avonex/and the other MS medications with Tysabri. I think the Tysabri has given me a second chance at helping slow my disease progress, but with out it I would be on no MS medications to slow the disease. I did alot of research before I decided to start the medication and the one resource that helped me make my decision was reading the Tysabri diaries on line. www.msrc.co.uk/index.cfm?
Avatar f tn I have had MD for 18 years. Been on Avonex, Betaseron, Tysabri, and now Tecfidera. Unfortunately, I'm also on lots of other medications, mostly due to terrible central pain. My neurologist made me stop the Tysabri after 24 infusions because of safety concerns. I felt my overall best while on Tysabri and have asked him if and when I might be able to go back on the monthly infusions. He does not have an answer for me at this point.
Avatar f tn Are any of you on Tysabri? My doctor has suggested that I consider starting Tysabri treatment. His neurology practice runs a TOUCH infusion center. I've been on Copaxone for four years and have just had my first flareup. My recent MRI shows progression of MS with T2 hyperintense white matter lesions in the pons of the brainstem and the frontal lobe. Several of the older lesions have increased in size. Five years ago I was on Avonex. I had multiple flare-ups the whole year on this med.
Avatar m tn I would like some information/details from anyone who has had (or seen) the rash you can get from Tysabril and/or PML?? I have been on Tysabri 10 years so far without any major issues. I was outside after my treatment for 10 minutes or so. After taking my shirt off, my husband gasped and asked what was wrong with my back.
572651 tn?1530999357 I've been tested twice in the last year, and they were both negative. Since you can acquire JCV at any time, I opt to have my status tested once a year since I'm on Tysabri. There is also a Tysabri antibody titre available, now. I plan on doing that once a year, too, although development of Tysabri antibodies is relatively rare.
Avatar f tn Now I am terrified that it was a melanoma and I have scrapped it off and the cancer will start growing without me knowing. Can you scrap off a melanoma? If it was a melanoma will the pigmentation grow to the surface again? Does melanoma heal? I know if I go to the gp they will not refer me to a dermatologist and can not afford to pay privately.
1827617 tn?1317703371 My new neuro suggested Tysabri based on increased lesions on Interferon (Rebif). Any persons out there on Tysabri that could share their experience?
Avatar n tn However, a mole I had on my forearm was indeed melanoma. Luckily it was melanoma in situ. It was a small mole (smaller than pencil eraser), flat, symmetrical BUT it had two shades of brown in it. Thanks! I'm two years out from my diagnosis and doing well.
Avatar n tn It is unrelated. Where is the melanoma in the eye? What type of surgery is planned? Dr. O.
572651 tn?1530999357 Cancer risk on Gilenya was mentioned here in a question and I asked that specifically. Two of the lab rats used to test Gilenya developed Melanoma, but they were on mega-doses that would never be given to human patients. They said they are not seeing this problem in humans. If you hope to become pregnant, they recommend that you be off Gilenya at least two months before they attempt to conceive.
1760800 tn?1406753451 He feels that Tysabri is the way to go. I know that there are others here on it or used to be. I would love some insight on what to expect, how long it takes, etc... Thanks!
1088527 tn?1425313375 I will start tecfidera in 3 months I hope I dont have the rebound effect I have heard about after stopping tysabri. Tysabri has really changed the way I feel was using a walker now nothing and I do Zumba too. I hope I stay like this but having doubts. anyone using tecfidera? How was your experience.?
Avatar f tn So now he wants to take me off of the Copaxone, I have been on for a month and a half, and put me on Tysabri. I started the application process and now waiting for them to call me and get the ball rolling on that. Now he mentioned that this is the top of the line MS medication so that does give me some relief. P.S. I did test negetive for the JC Virus. Any thoughts, experiences etc on this Tysabri??!!
1831849 tn?1383228392 The research side of my MS Practice has identified a CSF biomarker for disease activity. The research is featured on the cover of this month's Multiple Sclerosis Journal. http://tischms.org/news/tisch-ms-breakthrough-biomarker-research-featured-cover-article-october-2013-issue-multiple I'm a beneficiary of this discovery. I had been on Tysabri for 20 months. At 18 Months I converted to JCV +, and we discussed switching from Tysabri to Tecfidera.
Avatar m tn Hello, I had a suspicious mole on my neck removed in June and it came back as mild-moderate dysplastic nevus with differential diagnosis of early melanoma in-situ. The area was re-excised with 3mm margins. Since then I have had the slides re-evaluated by UPenn Dermatopathology and their diagnosis was Severe dysplastic nevus with differential diagnosis of evolving melanoma in-situ.
Avatar m tn I experience no signs (no night sweats, headaches, itching, etc) or symptoms of a recurrent Melanoma or even a secondary Melanoma. I have been looked over by 4 separate Dermatologists every 3 months for the last year and a half. I even had my Melanoma scar biopsied again for recurrence (negative). My Oncologist is pushing me to get a PET scan done. Now, I'm all for having a PET scan done if there is a high risk of cancer. All the tests I have had done have been extremely positive though.