tysabri liver function

Also, my neurologist says their is no data on how often to monitor liver function but that he plans to do bloodwork every three months like he did when I was on rebif. Any thoughts on this? Thanks in advance!

Hi all, My TOUCH center DOES monthly CBC, CD4 counts and liver function tests as a routine part of the Tysabri infusion experience. We see mid level practioners (MS Nurse Practioners) or the MD on a rotating basis so every 3 months I see the MD. Tysabri can cause liver dysfunction so they feel the testing is necessary to catch any developing trends. the CD4 counts and CBC they use to track treatment effectiveness.

I was on tysabri for 9 months till my liver decided it didnt like it anymore but I loved the drug went from using a cane to nothing. I just started gilenya yesterday so jury still out on that. Its been 7 months since being off therapy and feel like crap the fatigue is overwhelming and my balance is bad dragging foot again so should be using cane again just not mentally ready for it. if your jc neg I would go for the tysabri as long as insurance covers it 1 hr a month and done so easy.

The interferons may also cause problems with liver function (in a small minority, me included), hence the regular blood tests to keep an eye on this, which are not necessary with Copaxone.

Hey everyone went to my neuro today we are stopping tysabri due to liver enzymes elevated for last 3 months. Went to a GI specialist to rule any liver problems out and after all sorts of testing seems like tysabri is the likley cause. I will start tecfidera in 3 months I hope I dont have the rebound effect I have heard about after stopping tysabri. Tysabri has really changed the way I feel was using a walker now nothing and I do Zumba too. I hope I stay like this but having doubts.

I get the blood work periodically, but I always thought it was more liver function tests. Maybe they test for the NRBC's also, and I just don't know it... :-) All I know is that my labs have always come back good so far. Sorry I can't be of more help to you! And I'm sorry to hear that you are feeling bad in general. Does it seem like the Tysabri has helped with anything yet?

I had an aunt who died from liver cancer and her liver function tests were normal until the end stages. However, it is common to have cysts in the liver and fatty areas that aren't a problem. When I was dx they found a hemangioma in my liver and another cyst and there were two cysts in my kidneys. Before my surgery, I thought this must indicate cancer had spread there only to find out that most of us do have some sort of cyst congenitally or as we age. My dr.

Well, not only did my latest bloodwork show all my blood counts are good, but my liver function is now NORMAL!! Are you kidding me?? Its been a long time since that was the case. I couldnt believe it when my Dr said it. I could definitely get used to hearing that! Add to all that the fact that my side effects are minimal. The only thing I deal with on a regular basis is mild fevers. But Advil usually takes care of it.

My GGT on my Liver Function Test is very high. I am taking Phentoins for epilsepy and wonder if this is the cause.

2 yrs ago I had a Liver Function Test it was slightly elevated at 53 My doctor didn't seem worried, 9 weeks ago I had the test again and my doctor called me in to discuss it,It had more than doubled in 2 yrs to 116,does any one know if this is dangerous,and is it repairable now I've stopped drinking and the codeine.

I've got the results back of my liver function test,It has gone from 116 to 35 in 3 months,Doctors over the moon more excited than me I think.

In Total liver Function Laboratory Blood Test results (Alanine Amino Transferase Serum) conducted for Total Liver Function shows presence of low ALT or low SGPT levels of 14 . This result is quite below the range limits specified in the lab. test report which is between 17-63 .. Please intimate what will happen if it further reduces in the ALT levels and how to increase the ALT levels or how to come out from this problem . * Is it relates to early death of a person ?.

What supplements or other over the counter meds would you suggest to help improve my liver function? Also i think you should know i have had this disease for only two years now. Thank you.

I have had my liver function test and eye exam. Tomorrow I take my first dose and sit all day to be observed. I admit I'm scared but this may be my only alternative. Every MRI I get has many new lesions, however very little symptoms. I wonder if anyone else has tried this new drug yet?

Hi BL- Welcome to Our Merry Band :-) I was diagnosed 2 years ago, at age 51, with SPMS. My first, and up until a week ago my only, DMD was Tysabri. When I was diagnosed we were able to connect seemingly random events over the previous 20 years. What seemed completely unrelated was related. All were symptoms of MS. Because I'd had MS for so long my doc thought I was out of reach of the injectables. At the time the orals were just starting to come on the market.

I have failed rebif and my liver didnt tolerate tysabri after 10 infusions. I really didnt like the side effect profile from tecfidera and was hoping this was gonna get approved.

Last week I started my 3rd significant relapse this year, my specialist nurse is now talking about Tysabri. I was on Rebif for about 15 months and wasnt getting on with the side effects so I switched to Copaxone 6 weeks ago, which I'm quite happy with. I looked up Tysabri when I got home and all I got was all the bad news about the PML patients. They say that theres a 1/1000 chance of getting it, that seems quite high to me.

Hi, I just received my liver function test and am concerned. I am a social drinker who has no more than 2 glasses of wine maybe 4x a week (no hard liquor). My test results were GGT 105; ALT 154: AST 80...What does this indicate? This discussion is related to <a href='/posts/show/234245'>slightly elevated alt � ast</a>.

Friday I called my neuro to find out if they want me to do a washout period on Tysabri, as they are considering me for the new drug out in March. I've ben on Tysabri almost a year and JC+ from the start The nurse told me my test showed 1.03. which means nothing to me. Anyone know anything about this test?

Hope everyone is well. I just wanted to give an update. I had my first Tysabri infusion this morning and I experienced no side effects so far at all. Over the last 2 months I have had some improvment. I still have all my symptoms but they're less intense. So here's hoping for the best. Hoping this medication works at seriously slowing this beast way down. How are things with everyone? I truly hope everyone has been well or well as can be expected.

I am so worried now about liver disease and cirrhosis. If my liver was inflammed would doctor not have felt this at appontment as she said it was kidney? Would the ultrasound have to have showed liver problems for a LFT to be done or could this be routine ? If you have gall stones would a doctor check your liver function? If anyone can help i would be really grateful. I am so worried.

Tysabri liver function

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