tysabri depression

I walked (well limped) through the 5K walk for MS over the weekend, I used my cane and had lots of support from my team, I was feeling very smug about finishing. I went home after the walk and slept about 5 hours. I started feeling physical and mental fatigue at work yesterday. Also some depression, as if I just can't make myself be there. The stress and general commotion are just more than I can handle.

I have suffered through the fever, the body aches, let me make that severe muscle pains, abdominal pains, and the list goes on. The one side effect that is really worrying me is the depression. I have never been so depressed in my life. In fact I have never been what I would call depressed. I've have some really hard times but I've always been able to push through. Now I can't even get up to go to work. I cry over everything. I'm not a crier.

The best part for me, is that the interferons can make you prone to depression, if you are already pre-disposed to depression; which I was. You have to make sure when you are taking Interferons, that if you feel depression coming on, that is out of the norm for you, that you contact your doctor at once. It can be treated and still take the Interferon. Icing the area after the Copaxone injection can really help or some people say a moist hot washcloth on the area for about 10 minutes help.

Hello, I was wondering if I took tysabri with having MS also RSD because with having the rsd it does weakend my immune system, I don't believe this would be a very wise decision do you?

is recommending tysabri and I am not comfortable with this drastic of a change. I would like an opinion from my peers, I would like to know if any other of you have experienced this type of change in your personality. I went out of work on permanent disability as I could no longer perform executive functions and for that I am grateful, I was able to get out from under this horrible man. Who was fired later.

Do you know why your doctor wants to start you on Tysabri rather than one of the more first-line treatments?Tysabri is usually used when less 'extreme' measures haven't worked, or when secondary progressive MS is pretty clearly evident. Not saying that is how things work on paper, but in the real world most often T is considered only after other treatments have seemed to be ineffective.

Has anyone taking tysabri having any side effects such as jerking of the hands and legs? And extreme weakness of he legs?

Hi guys, I am not feeling to chipper these days. My UTI is back, and waiting for the full culture to come to decide what kind of anti-biotics we use this time. I am getting so worn out by all of this. The pain level in my body has doubled and I don't know if it is the e-coli or MS just kicking up it's heals. Got a call yesterday, and the nurses want me to go to the clinic to begin my Avonex injections next week.

At 20 months I had converted to JCV + and the Tysabri was no longer working. While on Tysabri I saw no change in my symptoms. As was said, that is no what any DMD is for. I had no ill effects of any kind.

In fact, my latest blood test turned up positive for JCV and my doc and I may need to start talking about switching away from Tysabri. That would suck! I love my Tysabri :-) What makes you want to avoid it?

They found out the reason people contracted PML was because they were taking Avonex/and the other MS medications with Tysabri. I think the Tysabri has given me a second chance at helping slow my disease progress, but with out it I would be on no MS medications to slow the disease. I did alot of research before I decided to start the medication and the one resource that helped me make my decision was reading the Tysabri diaries on line. www.msrc.co.uk/index.cfm?

The injections only work 33% if started at the beginning stages of Relapsing Remitting MS. There is Tysabri an infusion and their are drug trials for oral medications. Sometimes they can even use chemo but it is rough stuff. Unfortunately to date these are the only proven treatments. Some people go to other countries to get stem cells. The problem is stem cells can't repair damage they can only in some cases slow future damage but usually only for awhile.

I have had MD for 18 years. Been on Avonex, Betaseron, Tysabri, and now Tecfidera. Unfortunately, I'm also on lots of other medications, mostly due to terrible central pain. My neurologist made me stop the Tysabri after 24 infusions because of safety concerns. I felt my overall best while on Tysabri and have asked him if and when I might be able to go back on the monthly infusions. He does not have an answer for me at this point.

Are any of you on Tysabri? My doctor has suggested that I consider starting Tysabri treatment. His neurology practice runs a TOUCH infusion center. I've been on Copaxone for four years and have just had my first flareup. My recent MRI shows progression of MS with T2 hyperintense white matter lesions in the pons of the brainstem and the frontal lobe. Several of the older lesions have increased in size. Five years ago I was on Avonex. I had multiple flare-ups the whole year on this med.

I would like some information/details from anyone who has had (or seen) the rash you can get from Tysabril and/or PML?? I have been on Tysabri 10 years so far without any major issues. I was outside after my treatment for 10 minutes or so. After taking my shirt off, my husband gasped and asked what was wrong with my back.

I've been tested twice in the last year, and they were both negative. Since you can acquire JCV at any time, I opt to have my status tested once a year since I'm on Tysabri. There is also a Tysabri antibody titre available, now. I plan on doing that once a year, too, although development of Tysabri antibodies is relatively rare.

My new neuro suggested Tysabri based on increased lesions on Interferon (Rebif). Any persons out there on Tysabri that could share their experience?

My previous neuro was hypervigilent about depression and does a depression screening for every patient prior to prescribing any interferon, and annually thereafter. I dont know about my new neuro as I'm on Copaxone and not depressed so it ddnt ome up. My only eperience with Rebif was only a brief trial run due to elevated liver enzymes. I didn't have the other issues that you've had with it I'm sorry you're having such a rough go of it.

He feels that Tysabri is the way to go. I know that there are others here on it or used to be. I would love some insight on what to expect, how long it takes, etc... Thanks!

I will start tecfidera in 3 months I hope I dont have the rebound effect I have heard about after stopping tysabri. Tysabri has really changed the way I feel was using a walker now nothing and I do Zumba too. I hope I stay like this but having doubts. anyone using tecfidera? How was your experience.?

So now he wants to take me off of the Copaxone, I have been on for a month and a half, and put me on Tysabri. I started the application process and now waiting for them to call me and get the ball rolling on that. Now he mentioned that this is the top of the line MS medication so that does give me some relief. P.S. I did test negetive for the JC Virus. Any thoughts, experiences etc on this Tysabri??!!

The research side of my MS Practice has identified a CSF biomarker for disease activity. The research is featured on the cover of this month's Multiple Sclerosis Journal. http://tischms.org/news/tisch-ms-breakthrough-biomarker-research-featured-cover-article-october-2013-issue-multiple I'm a beneficiary of this discovery. I had been on Tysabri for 20 months. At 18 Months I converted to JCV +, and we discussed switching from Tysabri to Tecfidera.

side effects for each other medicine and now this with tysabri. Has anyone else been on tysabri and developed c. Diff from it? If so, what did they do to help it? Stop tysabri? Any information would be greatly appreciated.

Tysabri depression

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