Tysabri blood test

Common Questions and Answers about Tysabri blood test

tysabri

572651 tn?1530999357 The screening test for the JC Virus for patients considering Tysabri as their tretment was officially approved by the FDA today. The test tells if the person has been exposed to the JC Virus or not. PML on tysabri has only occured in people who are JC positive. There has not been a single case of PML in JC negative people. You can read the release here- http://www.medpagetoday.
1831849 tn?1383228392 This was another big Tysabri news story at ECTRIMS - researchers in Germany presented results on a blood test that identifies patients who will be safe on Tysabri, even if they are JC positive. http://bit.
233622 tn?1279334905 Good luck with Tysabri! I'm taking my 11th infusion on Wednesday. The good news, I haven't had any new flairs since I've been on it. I'm taking a "holiday" from Tysabri after this infusion. My neuro says a periodic holiday keeps the incidence of PML lower. I haven't had my JC virus antibody tested. Is this a blood test, or a urine test?
4848471 tn?1372238752 6 months ago my blood test came back JCV+. It had been JCV-. My CSF was still negative and we continued Tysabri. It is the only DMD I have ever taken. I'm seeing my neuro at the end of the month and we are going to discuss switching to Tecfidera. JCV+ is only one of the risk factors. You need to have at least one other. Even if you have all 3, the chances of developing PML are about 1.1% Here is some info from the FDA's website. (http://www.fda.gov/drugs/drugsafety/ucm288186.
Avatar f tn I had blood work done about 1 week before infusion #4 and found out last week that my tysabri antibodies test came back positive. Going tomorrow to see the dr for next step. Anyone have this experience of developing antibodies so quickly? What meds have been offered after tysabri?
147426 tn?1317265632 The equivocation comes from the occasional false negative of the JC blood test, so that the very rare person with PML and a negative result on the JC virus mostly likely actually has the virus which was not detected. There was some thinking that a Tysabri vacation could help prevent PML. I have not seen this evidence. Now - what I am about to talk about is not published and no one should act on it, but it is very interesting.
1638868 tn?1309542428 i have read up on tysabri and i dont like when i have read,they drew blood today to check for the jc virus.
Avatar f tn Last week I went for an MRI and blood test for the JC virus. I see my neuro Thursday to review these test results and decide on the Tysbari. I am sorry to be so self centerd and ramble on and on, but after reading your post, I am vert scared to try Tysbari. I am so looking forward to try something new and stop deteriating. Now I don't know what to do. I would really appreciate hearing from anyone else on Tysbari and hear how it as effected you.
Avatar m tn I hope you realize I wasn't trying to 'panic' anyone for any reason. I simply said that I am at the 'highest risk' for PML, cause I've HAVE had other meds for MS than just Tysabri in the past. I HAVE tested positive for JCV and I've been on Tysabri for over 3 years. Those are the facts.
Avatar f tn I sent you both messages about this. I have been following TY news since it came on the horizon for me. I do have quite a bit of info on it. Do you know that in development and scheduled to be released this year it has been published that a simple blood test to determine if & when PML has happened so treatment can begin early. Plasmorephis, blood filtering is already standard treatment to get Tysabri out of the body quickly if PML happens.
2047903 tn?1330187549 I too had my blood test JCV+ last month. My CSF was still negative. This means that I'm still OK Tysabri wise speaking. My neuro likes to reevaluate Tysabri use at 24 months. I had infusion # 18 last week. He thinks I would be an excellent candidate for Tecfidera. He said that if DMD'd were ranked from 1-100, in terms of 'power' Tysabri would be 100 and Tecfidera would be 75/80. As my MS seems to be pretty well under control. I may have needed Tysabri to get it under control.
Avatar f tn HOWEVER if you continue to test negative for the JC Virus there is no reason you should have to stop tysabri if it is working for you. In fact, stopping Tysabri is shown to cause serious relapses and is not something fun to go through. I would talke to a different doctor about tysabri and get off the holiday idea. Of course if you test positive for the JC virus, that is a different story entirely. good luck in working this through with your medical provider.
Avatar m tn I have annual JCV antibody tests, plus LP and MRI monitoring. Had the blood test last week (results unknown) and the LP and MRI in 2 weeks, I had my 15th infusion yesterday.
Avatar f tn I had so much bad luck in health lately and. Felt if anyone was going to get a fatal brain disease it was me. After imy blood test came back negative for the JVC virus my neuro assured me I couldn't get the disease with a negative result. I am monitored to make sure that doesn't change. It has been wonderful for me and after two months of fatigue that has passed, thank goodness!
1831849 tn?1383228392 -) It seems quite possible to have JCV DNA in your system but remain anti-body negative. In my last test, about 6 months ago, my blood antibody test came back positive, but my CSF remained negative. My Doc said it was OK to continue Tysabri for a wile. My inference was that JCV>PML does it's damage if it gets into your brain via CSF. I think that the bottom line is that you really can't rely on the old blood antibody test alone. You need to look deeper.
382218 tn?1341181487 I've been on Tysabri for 28 months and continue to test negative for the JC Virus, so it is a no-brainer for me. They screen for JC and liver function every six months but would do it more if I reguest. Kat mentions what I like best - besides that it is working for me - is this is just one day a month that I set aside to do my infusion and then I don't think about it again for another 27 days. I don't have that constant reminder with daily injections that I am sickl.
294425 tn?1288528395 t feel like it did anything for me. I would like to go back on Tysabri. My test level is actually very low. Do you know how high the JC Virus level has to go to be high risk for PML to set in?
Avatar f tn Has anyone ever had an occasional "off" day with Tysabri? I went for my infusion yesterday and usually they don't bother me at all but spent the rest of the day on the couch, with no energy and all day today with none. Can't remember having one like this in quite awhile and just wondering if anyone else had this occasional problem. Most of the time, its just like I got a saline injection!
1827617 tn?1317703371 My new neuro suggested Tysabri based on increased lesions on Interferon (Rebif). Any persons out there on Tysabri that could share their experience?