Tysabri antibody testing

Common Questions and Answers about Tysabri antibody testing

tysabri

Avatar f tn Hi SCG - That they showed up early may be a good thing. From rxlist.com: "Antibody testing: If the presence of persistent antibodies is suspected, antibody testing should be performed. Antibodies may be detected and confirmed with sequential serum antibody tests. Antibodies detected early in the treatment course (e.g., within the first six months) may be transient and disappear with continued dosing.
1831849 tn?1383228392 Food for thought for those on, or conteplating, Tysabri. Blood antibody testing for JCV may not be enough. http://www.medpagetoday.com/Neurology/MultipleSclerosis/39649?
233622 tn?1279334905 Good luck with Tysabri! I'm taking my 11th infusion on Wednesday. The good news, I haven't had any new flairs since I've been on it. I'm taking a "holiday" from Tysabri after this infusion. My neuro says a periodic holiday keeps the incidence of PML lower. I haven't had my JC virus antibody tested. Is this a blood test, or a urine test?
Avatar m tn I have MS and Neuropathy. I am currently on Tysabri. Previously I was on Betaseron and IVIG. When I went to Tysabri my doctor took me off IVIG and now my Neuropathy is worse, my feet and legs are on fire. Does any one know if it is safe to be on Tysabri and IVIG at the same time? My doctor said she would need to consult with other doctors before she would add IVIG to my treatment.
572651 tn?1530999357 I've been tested twice in the last year, and they were both negative. Since you can acquire JCV at any time, I opt to have my status tested once a year since I'm on Tysabri. There is also a Tysabri antibody titre available, now. I plan on doing that once a year, too, although development of Tysabri antibodies is relatively rare.
1713150 tn?1314467342 I have been hearing lots on this bored about this infusion thing w Tysabri. Since I am new at all this, I can't figure out exactly wat it is when I google it. Can someone please explain?? Very curious over here! Thanks!
1475492 tn?1332884167 9 (11/1000) Patients taking tysabri risk of PML with positive JC antibody and asecond risk factor (i.e. being on tysabri 24-48 months) 1/250 (4/1000) that does not mean you can not develope PML before the mmagic 24 mark. The risk just in creases at that point.
1168718 tn?1464983535 t know numbers yet, as nurse wants Neuro to tell me) There was apparently a note on my file that if it was positive that I was not to go on Tysabri. We never discussed this with her, and if the numbers are high of course I would not try it. , but, I know of people who are positive and low numbers and have done very well on Tysabri. I just want o give it a shot. I have to wait now till Wed. when my neuro is in and the nurse will chat with her as to what to do.
4848471 tn?1372238752 There is an alogirthm for the chances of contracting PML while on tysabri. I believe it is on the tysabri website among other places. I will see if I can find it for you and report back.
Avatar m tn There are a few more. Adrenal Cortex Antibodies also abbreviated 'ACA' 17-alpha-hydroxylase test and antibodies to the P450 side-change cleavage enzyme Together, these form a pretty comprehensive autoimmune test for adrenal autoimmune conditions. I was reading a paper on it that said up to 90% effective. But for being more thorough, you may also wanna consider Anti Pituitary Antibodies (APA) Those can mess up your ACTH production, leading to low cortisol.
Avatar n tn I had been on Tysabri for 22 month's and just recently stopped. I was wondering if any new info. is out there on the drug Rituxan for MS? I have SPMS with RRMS. I was in a study 3 yrs. ago at UCSF and did really well on Rituxan. However, Rituxan is not an approved drug for MS and at that time my insurance would not cover it so I had to discontinue taking it. Or should I just take a break for awhile and not take any ms med"s?
Avatar f tn Should it ever come to monthly testing for me, I'm lucky that my infusion center IS my neuro's office. At least the testing would be handled by qualified people.
147426 tn?1317265632 The Risk of PML is greatest in the setting of a positive J-lymphocytesC virus, greater than 24 months of Tysabri, and concurrent use of other DMD's or steroids. Those are old recommendations, and new info will change them in the (near?) future. PML is caused by the J-C Virus. A little more than half of all people have been infected with the JC virus. It generally lives asymptomatically in the brain unless something has occurred to cause the immunity of the brain to be compromised.
Avatar m tn Good day.......currently i m waiting my test result for my hep B antibody. The last 10months, i had tested my antibody and it said reactive means immunity to hep B. But some of my friends say i need to test again and dose it if my immunity below than average range. And also the immunity can decrease if i am contacting with the virus for many time. I m so worried coz one of my closely friend who have Hep B. Here is my question.... if my antibody is lower than reactive limit what should i do?
1950519 tn?1324518193 Hi. I'm a Tysabri user who thankfully has a negative JCV status. I'm on my 2nd year of this stuff, and I have no plans to stop anytime soon, because I haven't had a serious relapse since I've been on it (knock wood). I'll get my status tested once a year, and my neuro doesn't plan on more MRIs unless I change DMDs for some reason.
Avatar f tn According to my neuro, some people have this side effect since the drug does esstenially attack the body and it is trying to defend itself. They even ran antibody tests to see if I was allergic to Tysabri due to my blood work. However, I was NOT tired all the time. The othrs may have a valid point in that it may just be MS related fatigue you are experiencing. Do tell them when you go for your next infusion about your symptoms. Please keep us informed about how things are going for you.
198419 tn?1360242356 m more-so seeking clinical/scientific case reports that discuss various testing mechanisms when hypersensitive or anaphylaxis reactions were though to be cause by the interferon. Reason I'm asking is because my allergist has been doing some digging in order to develop a type of protocol to perform the challenge on me. She has not received any guidance from the company.
Avatar m tn The injections only work 33% if started at the beginning stages of Relapsing Remitting MS. There is Tysabri an infusion and their are drug trials for oral medications. Sometimes they can even use chemo but it is rough stuff. Unfortunately to date these are the only proven treatments. Some people go to other countries to get stem cells. The problem is stem cells can't repair damage they can only in some cases slow future damage but usually only for awhile.
Avatar m tn Duo contains an antibody test...