H.Pylori leads to Peptic Ulcer disease, which needs to be managed with 'Triple Therapy' consisting of Antibiotics(Amoxicillin and Clairithromycin), Proton Pump Inhibitors (Omeprazole or Rabeprazole), may also include Ulcer Protective Gels like Sucralfate,Irsogladine etc,antacids,Adjuvants like Okrin may also help.In case of resistant bacteria,Amoxcillin can be replaced by Metronidazole and other combinations of H2 antagonists and mucosal protective agents and multi vitamins help a lot.