Other than some serious weight gain (60 lbs. in 14 months), the effects
for me were nothing short of a miracle - suffering from Cyclothymia (lower level Bipolar, mood disorder, hypomania and acute insomnia), this was a miracle drug for me. I had tried all of the regular suspects: lamictal, topamax, trileptal, trazedone, geodon, invega (which caused a pituitary mass/tumor), etc. the Seroquel was what worked. I took 900mg at night, and was able to step down after all the weight to 300mg a night.