Some functional imaging studies, which can test brain activiation, blood flow, or
metabolism may show abnormalities, but these are most often done in the research setting and are not routinely available.
There is not definitive medical treatment for depersonalization and derealization however antidepressants such as SSRIs (prozac, lexapro, celexa, paxil, zoloft etc) and benzodiazepines (used for anxiety, such as valium, klonopin, ativan) have been used with some success in some patients.