barbie I have taken Ultram, Ultracet, Effxor, Neurontin, Lyrica, Flexeril and pain meds. All had side effects or made me sick because of UC and IBS. Right now only doing 5mils of Fexeril at night, 20 mils of Tranxene 3 times daily and tylenol. Helping with sleep problems, eases pain just a bit and keeps me calm. Problem though is sleepy, loopy minded, and balance is bad. If you do not have stomach problems Flexeril might help you if you take several doses daily.