In rare cases, high levels of serotonin in the brain may cause severe complications like seizures, stroke,
and even death. If venlafaxine
and tramadol are used
together, your doctor may want to closely monitor you for side effects. Ask your healthcare provider about these drugs and this potential interaction as soon as possible.
This interaction is poorly documented and is considered major in severity.
Here is a link to the web site:
http://www.drugdigest.