org/wiki/Tramadol#Uses
It has been suggested that tramadol could be effective for alleviating symptoms of
depression, anxiety,
and phobias[11] because of its action on the noradrenergic
and serotonergic systems, such as its "atypical" opioid activity.[12] However, health professionals have not endorsed its use for these disorders,[13][14] claiming it may be used as a unique treatment (only when other treatments failed), and must be used under the control of a psychiatrist.