Anticonvulsants tend to cause hyperinsulinemia (elevated insulin in the blood) and increased appetite leading to weight
gain. Hyperinsulinemia also results in increased testosterone
, which causes a risk to women on these medications for development of Polycystic Ovary Syndrome (POS). Polycystic ovary syndrome can cause weight gain, male pattern baldness, increased facial hair, skin tags, acne, infertility, high blood pressure, abnormal lipid levels, and heart disease.