Tenofovir analog

Common Questions and Answers about Tenofovir analog

viread

Avatar m tn Wanted to share, in case anyone was thinking of "stopping" after going undetected. I'm a little shocked that they had a relapse after seroconversion too....but it's clear Tenofovir (Viread) should be the drug of choice for many.
Avatar m tn Nucleoside/nucleotide analog antivirals such as tenofovir, entecavir (Baraclude), adefovir (Hepsera), and lamivudine (Epivir) are the mainstay of chronic hepatitis B treatment. Although they can effectively suppress hepatitis B virus (HBV) replication while on therapy, they typically do not eradicate the virus and therefore may need to be taken long term. Viral suppression has been shown to improve liver fibrosis and reduce the risk of complications such as liver cancer.
Avatar m tn change doctor right away, it does make no sense to prescribe these antivirals for a year and is of course only a damage for the patient the cure is about 17years of these antivirals or 5 to 10 years of tenofovir plus peginterferon add on to rescue immune system and clear hbv before 17years clearly this doctor doesn t know anything about hbv
Avatar m tn this remains the best strategy to clear hbv found until now and with highest rates, profund hbvdna suppression for years, tenofovir probably the best or tnf+etv, then add on of interferon the good thing is also a good decline of hbsag in almost all patients so interferon might be prolonged or stopped and restarted later
Avatar f tn http://www.fiercebiotech.com/biotech/geovax-draws-a-bead-hep-b-therapeutic-vaccine-deal GeoVax has partnered with Georgia State University to try to pursue an elusive goal—the development of an effective therapeutic vaccine for hepatitis B virus (HBV) infections. The treatment of chronic hepatitis B has improved dramatically in recent years thanks to new antiviral drugs, but efforts to develop a therapeutic vaccine have largely ended in disappointment.
Avatar m tn i got this from s stephen post in chinese forum Virologic breakthrough in a patient with chronic hepatitis B by combination treatment with tenofovir disoproxil fumarate and entecavir. Suzuki F1, Sezaki H2, Akuta N2, Suzuki Y2, Kawamura Y2, Hosaka T2, Kobayashi M2, Saitoh S2, Arase Y2, Ikeda K2, Kobayashi M3, Watahiki S3, Mineta R3, Suzuki Y3, Kumada H2.
215858 tn?1420171556 Sofosbuvir (brand name Sovaldi) is a nucleotide analog inhibitor that blocks a protein the hepatitis C virus needs to replicate." I tried researching this statement and was overwhelmed by the specifics. Could anyone explain it in simple terms? Thanks, V.
Avatar f tn Hi, if the viral load is greater than 20,000 IU/mL and HBeAg is negative then Interferon-alfa (Roferon A, Intron A), pegylated interferon-alfa (Pegasys, Peg-Intron), lamivudine (Epivir-HBV), adefovir (Hepsera), entecavir (Baraclude), tenofovir (Viread) or telbivudine (Tyzeka) may be used as initial therapy. There are standard protocols for therapy of hepatitis B infections, so you can clarify your doubts with your treating doctor. Regards.
Avatar m tn An extremely useful and clear research presentation that should clarify for many what to expect in terms of long term treatment in regard to surface antigen levels and amount of infected cells in the liver. It also shows again the slight but noticeable advantage of starting treatment with a combo, that can later be followed by mono therapy. Unfortunately the overall picture is not very encouraging in terms of loosing the infection.
Avatar f tn Our other clinical stage HCV candidates include PSI-7977, an unpartnered uracil nucleotide analog that has recently completed 28 days of dosing in a Phase 2a study, and PSI-938, an unpartnered guanosine nucleotide analog in a Phase 1 study. We also have in our pipeline an additional purine nucleotide analog, PSI-661, in advanced preclinical development. Racivir, for the treatment of HIV, has completed a Phase 2 clinical study. Pegasys(R) and Copegus(R) are registered trademarks of Roche.
Avatar m tn Berg presented interim 48-week findings; 21 participants in the stop-tenofovir group and 21 in the continuous-tenofovir group completed 48 weeks and were included in this analysis. Results At 48 weeks, patients who remained on tenofovir maintained viral suppression, had stable ALT levels, and none experienced HBsAg loss.
Avatar f tn That is actually not much better than tenofovir vs tenofovir disoproxil fumarate, the actual substance in Viread. It is 50 times more potent than tenofovir. It is all this improper simplification of callling viread tenofovir. Tenovovir, if it would be given orally, would have no effect on HBV. TEnofovir if given intravenously or sc would still have almost no effect on HBV in the liver. the substance has a high negative charge and cannot easlily penetrate cell membranes.
Avatar f tn (20) The T69S insertion mutations, associated with resistance to multiple nucleoside analogues, are associated with resistance to tenofovir as well. Tenofovir resistance conferred by the T69S mutation or by multiple thymidine analogue resistance mutations appears to be multiplied if the M184V mutation is replaced by wild-type.(21) The K65R mutation, which may be selected by prior nucleoside analogue therapy, is associated with a modest decrease in sensitivity to tenofovir.
Avatar m tn Association of Higher Plasma Vitamin D Binding Protein and Lower Free Calcitriol Levels with Tenofovir Disoproxil Fumarate Use and Plasma and Intracellular Tenofovir Pharmacokinetics: Cause of a Functional Vitamin D Deficiency? "The finding of a 26% increase in vitamin D binding protein and a 42% decrease in free 1,25-OH(2)D between the lowest and highest quintiles of plasma tenofovir has not been previously reported.
Avatar n tn The following is a paper from doctors in Francel. It said you can breastfeed whilst your are on Tenofovir because "Tenofovir is not absorbed in the breast milk". However, I have googled and cannot find any reference to this claim. All the best to you and your baby. Clin Res Hepatol Gastroenterol. 2011 Jun 7. [Epub ahead of print] Hepatitis B virus infection and pregnancy. Pol S, Corouge M, Fontaine H.
Avatar m tn Hi stef good day. U still there?? I have some question stef about taking tenofovir because i dont know what to do. Im start taking tenofovir september 2020 and i notice that february my urine have bubles until now my urine still foamy or bubles but in evening is normal. Tenofovir can cause proteina stef??
Avatar n tn tenofovir, no resistance entecavir, 1,5% resistance but cannot be used on those using lamivudine because in this case resistance can go higher than 50% interferon if i had a doctor prescribing me such rubbish useless toxic.....i d destroy his life....
Avatar m tn I am on tenofovir from March 2012 when i am pregnant at week 32. At that time i had hbs and hbe both positive.
Avatar m tn Hi All, Is there a way I can have a prescription from a doctor when buying tenofovir online? Here in the Philippines, the drug is not yet available and the doctors are not prescribing it since it is not available. I'm planning to take tenofovir but having trouble in getting prescription, so i cannot order online. Please advise.
Avatar f tn I took tenofovir from the 3rd trimester and my baby is fine till now but i stopped using it when she 2 months and start again 2 days ago since.
Avatar m tn hbv has no symptoms, you may even be dying and feel nothing tenofovir improves kideys function especially tenofovir+telbivudine in those with kidneys function.
Avatar m tn http://pharmacychecker.com/Pricing.asp?DrugName=Tenofovir+Disoproxil+Fumarate&DrugId=59463&DrugStrengthId=105019 or http://www.northdrugstore.com/buy-Viread.html maybe this will help ... but have to check before because some fake drugs can be sell over the internet.