Telmisartan pharmacokinetics

Common Questions and Answers about Telmisartan pharmacokinetics

micardis

Avatar m tn IS THERE ANY SIDE EFFECTS TAKING COMBINATION OF TELMISARTAN &AMLODIPINE FOR LONG TIME
Avatar n tn - Absorption, oral: time to peak concentration 7h - Elimination half-life = 12 h (It says also that in general it can be administered once daily because it has a 24 h effect.Why?) - Can you give another example to clarify it better please? - When it says divide in 2 doses , does it mean only in the morning and dinner? 3 doses (morning-lunch-dinner)? Thank you for taking the time to answer!!
Avatar m tn I am 33 year male having hypertension from 3 years taking telmisartan 40 mg from last two years.Now my bp is under control comes under 130/85. I had urine albumin excretion test three times result shows between 100 to 75 mg/dl albumin excretion ( 24 hour urine albumin test on submission of around 1.5 liter urine).The normal values shows in lab report is up to excretion of 150 mg/dl/ .My serum creatinine level comes between 0.8 to 1.0 and urea under 20.
Avatar n tn Your creatinine is still high because you likely have chronic kidney disease from the hypertension. The Telmisartan-HCTZ that was given will not make your creatinine low, it is to treat your hypertension and prevent further damage to your kidneys. It is also possible you have some protein in your urine which the Telmisartan helps to reduce. Also, Telmisartan can cause a slight increase in your creatinine but it is usually not a very significant increase.
Avatar m tn p in my 19 14mnths bck at that time my b.p was 230/124 its over 200 fo 3 days then i started using telmisartan 40mg nd meoprolol 25mg bt my bp ranged 150-160/104-115 fo 8 mnths in btwen i was evaluated for 2ndry causes of hyp no resns wer found doc said its essenstial hyp then doc incresd telmisartan to 80 mg my systolic came to 140 mm/hg bt diastolic still ranging 100-110 why is it so high nd how to regulate it ?
Avatar m tn My BP stays around 170/100. Highest was recorded 176/110. I have been on Telmisartan 40mg for few weeks but it killed my sex drive entirely. I stopped taking it & gradually recovered from low libido. Also i've noticed a general decline in libido & an onset of ED after i crossed age 40. Now my libido is not that strong as it used to be 4 years back even without medicine.
Avatar m tn Also, she is patient of high blood pressure. She is on bloog sugar medications like Metformin, Glimipride and Telmisartan, Amlodipine tablets for high bp Daily. Now, she has many complications of Diabetes including Diabetes Neuropathy, eyes issues like cataracts, osteoarthritis etc. she also has complications in her back/spine. Now, her doctor has not recommend any special multivitamin apart from diabetic die,t.
336017 tn?1263579257 the best ARB to take is probably telmisartan because of its high tissue penetration. The best ACE inhibitor to take is perindopril. Some other ARBs and ACE inhibitors may work less effectively or not at all (some ARBs I know to be good - besides telmisartan - are valsartan, irbesartan, candesartan. Most of them are good EXCEPT for losartan, which is a surmountable antagonist and, theoretically, would lose its effect over time). Next fact: you need to take a high dose.
Avatar f tn You take metoprolol, diltiazem, enalapril and telmisartan. The first two agents address primarily heart rate (HR) but are not great blood pressure (BP) drugs. Speaking of HR, what is the reason that you see an electrophysiologist? Atrial fibrillation? and are you feeling poorly when your heart rate is 40s?
Avatar m tn I ended up on a prescription of 40mg of Telmisartan and 2.5mg of Nebivolol daily, and a diuretic which was cancelled by my Doctor. The Telmisartan was pared back to 20mg some time later after my readings were getting too low. My BP is around the ideal 120/80 mark and my resting pulse is normally around 50 but sometimes gets as low as 45.
Avatar m tn I can't help out on the pharmacokinetics, but your reasoning is sound: it doesn't make sense to dose so that the drug runs out. I'd query Schering-Plough as well as your hepatologist, if I were you. Please give me a heads-up if you solve the riddle.
Avatar m tn I am hypertensive for the last 2-3 years and had a BP of 150/100. The doctor has now put me on Telmisartan 40 mg and Amlodipine 5 mg (it is one tablet per day) for 2 weeks. My BP has now reduced to 140/80. I was asked to take a 2D echo and a tread mill test yesterday and here are the findings : 1. 2-D Echo findings - Mild LVH. LVID-d : 3.92mm, LVID-s : 2.06 mm, LVPW-d : 1.22 mm, LVPW-s:1.64 mm, IVS-s : 1.11 mm, IVS-d : 1.27 mm, EF-70%. Normal LV Systolic function (EF 70%).
Avatar f tn Bp was still not getting controlled and i was started on telmisartan and also amlodepin along with the metoprolol. The bp was then controlled well for about 3 months, however the anxiety continued. Since the last week my bp is also increasing to 140/90 along with the anxiety and also i am experiencing what i think is hot flashes. Can you please explain the connection between these symptoms and their relation to menop[ause. What can a person do about the same .
7510956 tn?1411671417 //www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials/drugs/antiviraldrugsadvisorycommittee/ucm375286.
Avatar n tn My doctor put me on a medicine called Micardis HCT which is a combination medication with the common diuretic hydrochlorothiazide and the drug telmisartan. This is the first time I have been on blood pressure medicine, and the drug has worked very well in terms of my blood pressure itself. I take my pressure at home with an electric blood pressure monitor and I now average about 130 over 72 to 75.
Avatar m tn Hepatic Impairment In volunteers with hepatic impairment (Child-Pugh Class A and B), sildenafil clearance was reduced, resulting in higher plasma exposure of sildenafil (47% for Cmax and 85% for AUC). The pharmacokinetics of sildenafil in patients with severely impaired hepatic function (Child-Pugh Class C) have not been studied. A starting dose of 25 mg should be considered in patients with any degree of hepatic impairment [see Dosage and Administration (2.5) and Clinical Pharmacology (12.3)].
Avatar f tn Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough..." It however says that initiation of Folic acid and phenytoin together is beneficial. Since you can't go back and start all over again, you can take a small dose. It has been observed that as los as 1mg dose can perturb phenytoin’s levels, You may take doses lower than 1mg/day.
863754 tn?1239144755 However, physiological changes resulting from smoking cessation may alter the pharmacokinetics or pharmacodynamics of insulin; dosage adjustments may be necessary.
Avatar n tn I get that dry cough too. I don't take an ACE inhibitor though, I don't think. Just Lopressor, Dyazide/Maxzide, Lipitor and aspirin for the heart issues. For me it started a couple of years ago one summer after pushing myself too hard. I start coughing out of the blue to the point of either just about passing out or vomiting mucus. Urgg My chest hurts and feels sunken in, pounds very hard and quivers sort of and then I'm fine till it happens again.