Telmisartan bioavailability
Common Questions and Answers about Telmisartan bioavailability
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IS THERE ANY SIDE EFFECTS TAKING COMBINATION OF TELMISARTAN &AMLODIPINE FOR LONG TIME
I am 33 year male having hypertension from 3 years taking telmisartan 40 mg from last two years.Now my bp is under control comes under 130/85. I had urine albumin excretion test three times result shows between 100 to 75 mg/dl albumin excretion ( 24 hour urine albumin test on submission of around 1.5 liter urine).The normal values shows in lab report is up to excretion of 150 mg/dl/ .My serum creatinine level comes between 0.8 to 1.0 and urea under 20.
Your creatinine is still high because you likely have chronic kidney disease from the hypertension. The Telmisartan-HCTZ that was given will not make your creatinine low, it is to treat your hypertension and prevent further damage to your kidneys. It is also possible you have some protein in your urine which the Telmisartan helps to reduce. Also, Telmisartan can cause a slight increase in your creatinine but it is usually not a very significant increase.
p in my 19 14mnths bck at that time my b.p was 230/124 its over 200 fo 3 days then i started using telmisartan 40mg nd meoprolol 25mg bt my bp ranged 150-160/104-115 fo 8 mnths in btwen i was evaluated for 2ndry causes of hyp no resns wer found doc said its essenstial hyp then doc incresd telmisartan to 80 mg my systolic came to 140 mm/hg bt diastolic still ranging 100-110 why is it so high nd how to regulate it ?
Atorvastatin is supposed to be one of the two most effective statins in lowing cholesterol so you are on a good one. Bioavailability is how well a med is absorbed and used by the body and bioavailability varies among the statins. It's actually a desired thing. The liver is the target organ so if it is slowed down in the liver (where this happens), it's in the target organ. But honestly, that is hard for me to understand.
My BP stays around 170/100. Highest was recorded 176/110. I have been on Telmisartan 40mg for few weeks but it killed my sex drive entirely. I stopped taking it & gradually recovered from low libido. Also i've noticed a general decline in libido & an onset of ED after i crossed age 40. Now my libido is not that strong as it used to be 4 years back even without medicine.
Also, she is patient of high blood pressure. She is on bloog sugar medications like Metformin, Glimipride and Telmisartan, Amlodipine tablets for high bp Daily.
Now, she has many complications of Diabetes including Diabetes Neuropathy, eyes issues like cataracts, osteoarthritis etc. she also has complications in her back/spine.
Now, her doctor has not recommend any special multivitamin apart from diabetic die,t.
Although a standard meal did not affect ribavirin bioavailability (F1), administration of ribavirin with a high-fat meal increased bioavailability by 46% relative to the fasting state. A high-fat meal prolonged the duration of the zero-order input part of the absorption model, with D1 increasing from 0.498 h (fasting and standard meal) to 0.740 h. The type of meal also influenced the first-order input part of the absorption model (Table 1).
You take metoprolol, diltiazem, enalapril and telmisartan. The first two agents address primarily heart rate (HR) but are not great blood pressure (BP) drugs. Speaking of HR, what is the reason that you see an electrophysiologist? Atrial fibrillation? and are you feeling poorly when your heart rate is 40s?
When a medication is administered intravenously, its bioavailability is 100%. However, when a medication is administered orally, its bioavailability decreases because not all of it is absorbed. So 70% bioavailability means that, from the dose you took, 70% of it reached systemic circulation.
"Two studies have been carried out to assess the effect of food (ie, a high-fat breakfast) on the bioavailability of a SINGLE oral dose of ribavirin. An initial study by ICN Pharmaceuticals, Inc.
Also as a side note, Opana oral bioavailability is actually very low. Lower than morphine I believe the bioavailability is around 10 percent. However, if you reach your optimal dose, bioavailability matters little.
I see that this post is from October 2011. But since I have this typed, I'll post anyway :) Good luck and gentle hugs.
Blood tests are not accurate for testing the active bioavailability of sex hormones in the cells and tissues. They only test what's in the blood stream. They aren't accurate for testing when a patient is using bioidentical topical creams. I've had two holistic doctors tell me this and have read numerous articles about which testing is correct depending on which type of hormones you're taking.
The ascorbate in Ferrous Ascorbate helps retardation or prevention of Fe(II) oxidation by ascorbate and to the existence of Fe(II) as a chelate with ascorbate ( vitamin C if you like ). Ferrous Ascrorbate will have a better bioavailability but you can add a vitamin C and vitamins B complex with sodium feredetate and have pretty good results.
Depending on your needs; are you lacking iron? anemia?
I ended up on a prescription of 40mg of Telmisartan and 2.5mg of Nebivolol daily, and a diuretic which was cancelled by my Doctor. The Telmisartan was pared back to 20mg some time later after my readings were getting too low. My BP is around the ideal 120/80 mark and my resting pulse is normally around 50 but sometimes gets as low as 45.
The component of the final population pharmacokinetic model that describes the absorption phase is complex. Although a standard meal did not affect ribavirin bioavailability (F1), administration of ribavirin with a high-fat meal increased bioavailability by 46% relative to the fasting state. A high-fat meal prolonged the duration of the zero-order input part of the absorption model, with D1 increasing from 0.498 h (fasting and standard meal) to 0.740 h.
I am hypertensive for the last 2-3 years and had a BP of 150/100. The doctor has now put me on Telmisartan 40 mg and Amlodipine 5 mg (it is one tablet per day) for 2 weeks. My BP has now reduced to 140/80. I was asked to take a 2D echo and a tread mill test yesterday and here are the findings :
1. 2-D Echo findings - Mild LVH. LVID-d : 3.92mm, LVID-s : 2.06 mm, LVPW-d : 1.22 mm, LVPW-s:1.64 mm, IVS-s : 1.11 mm, IVS-d : 1.27 mm, EF-70%.
Normal LV Systolic function (EF 70%).
Bp was still not getting controlled and i was started on telmisartan and also amlodepin along with the metoprolol. The bp was then controlled well for about 3 months, however the anxiety continued. Since the last week my bp is also increasing to 140/90 along with the anxiety and also i am experiencing what i think is hot flashes. Can you please explain the connection between these symptoms and their relation to menop[ause. What can a person do about the same .
Thank you for your question,
Yes, it is recommended you take it in the morning on an empty stomach, at least 30 minutes before food. Taking levothyroxine with food may cause reduced bioavailability and may lower drug levels leading to signs or symptoms of hypothyroidism. In addition, cottonseed meal, walnuts, and dietary fiber may decrease absorption of levothyroxine from the GI tract.
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