tamiflu renal dosing

Please note Tenofovir is principally cleared through the kidney and dosing adjustments due to renal impairment have not been clinically tested. The followings are extracts from the label information for Tenofovir: 2.3 Dose Adjustment for Renal Impairment in Adults Significantly increased drug exposures occurred when VIREAD was administered to subjects with moderate to severe renal impairment [See Clinical Pharmacology (12.3)].

I am not aware that impaired renal function precludes treatment for HCV. I have read that kidney disease is a negative predictor of SVR but, so too are a lot of conditions yet people have overcome them. I have seen articles which discuss the plasma levels of ribavirin with renal impaired patients. The suggestion is that rather than weight base dose these patients the dose should be arrived at by considering GFR (glomerular filtration rate). This is from Clinical Care Options @ http://tiny.

By "AGE" I'm assuming you mean a persons age in years. I don't believe age has anything to do with Janumet's "effectiveness" but age has a larger role with renal function. To make it clear for other readers, Janumet is combination of two drugs; Sitagiptin and Metformin. This a brief from the Merck web site - makers of Janumet - Section 8.5 - Geriatric Use JANUMET.

I also have kidney damage from a bout of high blood pressure 4 years ago, and I am a frequent kidney stone former, so I am being watched carefully by a nephrologist too. I have renal panels frequently too. I was wondering if any of this could increase my stone risk. I was reading about the cytomel and stones. The nephrologist wants me to remain on the synthroid and cytomel.

I think it depends on some individual factors, particularly renal clearance of the drug. I found this information in the drug reference: According to the manufacturer's tests, the drug reaches maximum serum levels between 15 and 44 hours after subcutaneous injection of a single dose. The mean elimination half-life is 22 to 60 hours (mean = 40 hours). So, I would expect that after 7 days (4.2 half-lifes) that the concentration would be about 5.5% (0.5^4.2) of the maximum levels.

30 weeks pregnant, has anyone ever took tamiflu while pregnant? Any side affects to you or your child after birth?

I am 5 weeks pregnant with my 3RD baby. I came down with a cold on Thursday. My cough is horrible and I have been running fevers a lot. I called my OB and she called in a RX for tamiflu. I've never been on it before but she assured me that it was safe. She said my cough may turn into pneumonia or bronchitis and that may be worse then taking the meds. I never went thru this with my boys so I'm a little unsure. I did research and it seems safe. What are others opinion on this.

My four-year-old grandson, who has leukemia, was just diagnosed with the flu despite having the shot this year. I also had the shot prior to my diagnosis. Obviously it doesn't cover strain B, which is what he has. My husband and I kept him until this morning so we have been exposed big time. Does anyone know about Tamiflu and whether or not it should be taken with HCV. My guess is it's okay, but my hepa will not respond to any of my questions, so I'm asking here.

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I am currently 16 weeks pregnant and just found out I have the flu. My OB put me on Tamiflu but my primary said she wasn't sure about it. Has anyone been on this while pregnant? I'm worried it's going to hurt the baby. Also it did get the flu vaccine, I was only a couple weeks pregnant so I didn't know but I'm a little mad they push a vaccine that obviously doesn't work.

told us that he was not eleigible to recieve a prescription for Tamiflu. Where can I find any federal or state restictions for eleigibility.

Glomerular filtration rate or its approximation of the creatinine clearance are measured whenever renal disease is suspected or careful dosing of nephrotoxic drugs is required. The normal ranges of GFR, adjusted for body surface area for males is 70 ± 14 mL/min/m2 (56-84) . Risk factors for kidney disease include diabetes, high blood pressure, family history and older age. Take care and keep us posted.

Yes I took tamiflu when I was pregnant with my son it's on the lowest scale for harming you or the baby. In other words its safe.

My OB called me and told me that as a prevention she wanted to put me on Tamiflu which is not recommended for pregnant women because the side effects are unknown. She said that the benefits would outweigh the negatives most likely because there have already been deaths linked to this strain of flu. The pharmacist didn't seem worried because I am 18 weeks along. Any of you ladies been put on tamiflu? Should I trust my doctor and pharmacist?

OB says to take Tamiflu and start today, but Tamiflu is not recommended for pregnancy based on unknown reactions to unborn children. Hubby and I don't know what decision is the best for us. Any opinions? The prescription is waiting for me...just so scared either way. I am leaning towards taking my chances and not taking it, but that is not the recommendation. What if I harm my baby by taking it? What if I do by not taking it??

Get to a doctor and get a tamiflu prescription asap if you test positive. It took me almost a month to recover.

ll cause harm to my baby. Anyone been prescribed meds for flu this pregnancy? (Tamiflu in particular..) Any natural remedies? That's the route I like to go.. I've never had the flu in my life.

I ended up in urgent care where they told me i got the deadly kind of flu. He prescribed me Tamiflu and was wondering if anyone else has taken it. Did you experience any side effects to you or baby. I am worried about my baby.

For the last four days I been having flu like symtoms (fever, night sweats, body aches) , seen the dr. and he perscribed TAMIFLU. In what time frame would someone infected see symptoms if any at all? 2. Would you suggest testing and if so what test would be the correct test at 9 weeks. Would TAMIFLU affect the result?

ve super sick since yesterday went in to the er tonight and was told i have the h1n1 infuenza they told me i have to be put on medication wich is tamiflu but i am so scared for my baby I'm am 31 weeks pregnant and have two other kids has anyone experience this while pregnant and took that medication was it safe for baby?

I was diagnosed with influenza on sunday in the er and the doctor prescribed me with tamiflu 75mg but I'm worried about my baby getting harmed by the medication because I'm only 14 weeks...any comments or recommendations???

Tamiflu is in no way safe during pregnancy. The risks outweigh the benefits I'm pretty sure.its class c. I had flu last January 7 months pregnant and they couldn't give me anything. But tell me to stay hydrated!!

My husband and MIL had the flu over Christmas, but I had a flu shot and was fine. You can take Tamiflu while pregnant if you do get the flu.

I have been so miserable for a whole week now. There is no relief and at times I feel like I'm dying. This might sound dramatic but I am serious my nose runs like a faucet I cannot breathe through it my TEETH hurt so bad I can't chew a banana. My throat and mouth are on fire because of all the mouth breathing and the aches pains and chills are enough to send me up the wall! I have never had the flu before but I wouldn't wish this on Hitler!

There are preferred opiates drugs that are use in patients with liver disease that have shorter half-lives and have less harmful side effects on the renal system. Your liver doctor should be aware of these drugs and be able to determine if you may be able to use them. With regards to OTC medications, normal recommended doses of acetaminophen can be safely given to patients who suffer from cirrhosis in the short term.

Tamiflu renal dosing

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