Though low IGF-1 is associated with low growth hormone, inactive/ineffective forms of GH, and low pituitary function, it may be related to nutritional deficiencies, chronic
kidney or liver
disease,
and with high doses of estrogen. Since cortisol is also low, low pituitary function is a possibility. Since you are gaining weight, anemia, nutritional deficiencies, liver and kidney disease may co-exist. A comprehensive investigation is required keeping all the points in mind.