Our data highlight the potential of direct innate immunity activation in hepatocytes in the control of HBV replication, and support the recent interest in the development of PRR-based antiviral strategies against HBV. In addition, our data suggest that elucidation
of the
mode of antiviral
action of imiquimod may lead to the identification of a novel target for the treatment of CHB.
Disclosure of Interest: J. Lucifora: Grant: Gilead, S. Maadadi: : None Declared, O.