Extreme sensitivity to skin and heightened painful response to pressure could be due to fibromyalgia, post herpetic neuralgia caused by shingles and chicken pox. Certain other conditions which cause the skin
painful to touch
are chronic fatigue syndrome, deficiencies of vitamin B1, B2, B6, migraine, and tactile defensiveness. Tactile defensiveness is caused by midbrain defect.
Post spinal fusion may be responsible if certain nerve roots are damaged or entrapped.