Sitagliptin sulfonylurea
Common Questions and Answers about Sitagliptin sulfonylurea
januvia
glipizide is in the Sulfonylurea class of drugs. Sulfonylurea drugs work by forcing the pancreas to make more insulin, insulin lowers BG. So if you dont eat and continue to take glipizide you run the risk of getting hypos. I say the risk as it depends what your BG is and how much glipizide lowers your BG.
If you are on glipizide you should have a BG test meter to check your BG. So test to see how your BG is doing.
m asking please if is it possable that if i take the drug sitagliptin it would mean i could reduce the gliclazide and stop the mrtformin my Diabetes is well controlled on the whole but my nurse as requested i increase the glicazide
Of the total number of subjects [N=3884] in Phase II and III clinical studies of Sitagliptin, 725 patients were 65 years and over, while 61 patients were 75 years and older. No overall differences in safety or effectiveness were observed between subjects 65 years and over and younger subjects. While this and other clinical experience have not identified differences in responses between the elderly and younger patients, greater sensitivity of some older individuals cannot be ruled out.
Other interactions
During concomitant treatment with hydantoin derivatives(phenytoin), the serum hydantoin concentration may rise. Acitrom may potentiate the hypoglycaemic effect of sulfonylurea derivatives. Since neither the severity nor the early signs of interactions can be predicted, patients taking Acitrom, especially if they also suffer from hepatic dysfunction, should limit their alcohol intake.
This interaction details are taken from http://www.health.gov.
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