My IGE level is 225, I want to know what that means as to severity. I have been on Xolair for one year, 300mg every two weeks, and I don't feel as if it has helped. I am considering stopping treatment due to no change. I am on Advair 500\50, Singulair 10mg, Spiriva, Claritin, Albuterol (both by nebulizer and fast inhaler) prednisone every month, for the last 2 years and I don't feel any better.