Sinemet hyponatremia
Common Questions and Answers about Sinemet hyponatremia
janumet
My father has had RLS for years and taking Sinemet to control it. Lately he has been acting differently almost like he has no control over his arms, mouth and legs. Can taking Sinemet for a long period of time cause Parkinson or similar disorders?
5-6 years ago, she started parkinson treatment as 3 per day 25/100 sinemet. Half year ago, her motion slows down, drooling a lot. Sinemet was increased to 3 per day 25/250. it really helped at first. 2 months later, dyskinesia occurred in tongue/jaw, drooling returned. Sinemet dosage then was decreased to 2 per day 25/250 (9am, 2pm), Requip 0.125 (9pm). Dyskinesia improved. 1.5 month ago, teeth grinding started day and night.
"We also asked if he had any other patients showing similar symptoms after taking Gleevec but got no response. "
Well, from the cited article "Electrolyte Disorders Induced by Antineoplastic Drugs", we have:
"In cancer patients, hyponatremia has an overall prevalence up to 47% with mild, moderate and severe degrees accounting for 36, 10, and 1%"
So while severe is rare, overall is not at all rare.
I started taking Sinemet about 3 months ago and my blood sugar levels, insulin resistance are all over the map. In the morning I fight to get my BSs down and now, in the afternoon, I often have BS crashes into severe hypo territory. I've been to the emergency twice these past two weeks - a week ago Friday with hyper, ketones and this last Friday with a severe hypo with 5 units still active!!!
I hated that because it worked so well, but side effects were intolerable. This as of April 28th. Was started on Sinemet. Was told this does not work as well as Requip, but was less likely to have same side effects. Said he could add darvocet if necesary.Also take ativan 1mg 3 x daily since the brain surgery, and 1-2 at night for help with sleep. Every other sleep aid made above symptoms worse. Did tapered Requip withdrawal while adding the sinemet.
I hated that because it worked so well. This as of April 28th. Was started on Sinemet. Was told this does not work as well as Requip, but was less likely to have same side effects. Said he could add darvocet if necesary.Also take ativan 1mg 3 x daily since brain surgery, and 1-2 at night for help with sleep. Every other sleep aid made morning "miseries"symptoms worse. Tapered Requip withdrawal while adding Sinemet. Right now taking 1/2 afternoon and 1 at night.
Hyponatremia is a common electrolyte disorder defined as a serum sodium level of less than 135 mEq per L. Treatment is based on symptoms and underlying causes. In general, hyponatremia is treated with fluid restriction (in the setting of euvolemia), isotonic saline (in hypovolemia), and diuresis (in hypervolemia).
For more information, see Figure 1 and Table 1 in the following article:
https://www.aafp.org/afp/2015/0301/p299.
My doctor prescribed Sinemet (generic name: carbadopa/levo) 25/100mg each night, and I no longer have restless legs. I've been taking it for about 4 years now, and as far as I know, I don't have any negative side effects from it. (I know you said you prefer to balance yourself without pharmaceuticals, but if you don't find a way to do that, the Sinemet really works for me.) Sleep is SO important.
I too have been on both of these meds and have had similar issues. Have you been on Sinemet yet? Requip and Mirapex are dopamine agonists, but Sinemet is a dopamine replacement and is best reserved for when the agonists no longer work.
SinemetCR worked for me for a few years before the side effects outweighed the decreasing benefits. It's more complicated to optimize it's effectiveness, as one is best served to consider the timing, volume and content of their meals.
If you have hyponatremia maybe. Did they do a blood test? How long did they say to eat more then average sodium?
I've been dealing with horrible spasticity since April and has gotten worse. I don't sleep much anymore at night and I work full time. My MRI shows no changes (minimal) and thoracic spine has no lesions. I've tried so many medications including sativex. I'm so tired and done with it all. I've also tried amitripyline, carbonmezipine, sinemet, quinine, nabilone and nothing. Please help....
What would be a rough formula for calculating sodium excretion. This has to handle extreme results like acute hyponatremia and hypernatremia.
What is the maximum excretion at which point the body is unable to keep up with consumption?
This information will not be used for any actual medical purpose on any actual organism, inaccuracy is acceptable and even intended to keep the calculations simple.
t know if it is from the meds... as far as the meds. Sinemet and I just quit Nuepro...
This discussion is related to <a href='http://www.medhelp.org/posts/show/227738'>hard bump under left armpit</a>.
I’m not taking any medication from beginning of January (I suspended Sinemet and Amantadine, as recommended by my neurologist due no visible effects on my condition).
I have been on courses of prendisone for a repetitive chest infection for the past 12 months and I am still using a steroid inhaler. I am also on sinemet 500 for my Parkinsons condition. What could be the cause of the sudden increase in heart size. I am 72 years young.
Hi,
Drinking too much water can lead to a condition known as water intoxication and to hyponatremia. This is most commonly seen in infants under six months of age and sometimes in athletes. This also results when a dehydrated person drinks too much water without the accompanying electrolytes.
Excess water outside the cells draws sodium from within the cells out to re-establish the necessary concentration. As more water accumulates, the serum sodium concentration drops , hence, hyponatremia.
On August 23rd, 2014, he was diagnosed with Tonsillitis, Hypertension, Hyponatremia, Hypokalemia and Hypoxemia by one hospital.
I'd be concerned about the Sinemet because that eventually does cause tardive dyskinesia. I'm assuming what you have is a temporary movement disorder such as akathesia. There are a fair amount of side effect pills that won't worsen it. Inderal and Atenolol are particular good for tremors. Atenolol is the most tolerable of the two as I and other people have found.
His nails are short and kept trimmed. He is on Coreg,Lantus,vit c,multivits and zinc. As well as synthroid and sinemet. We would love to help alleviate this itching sensation and protect his skin. any suggestions.
Check for hyponatremia, it sounds like potential symptoms of hypoadrenalism. Do you crave sodium at all?
Then she got ill and stopped when she was admitted to the hospital for low sodium/high potassium levels and was given an IV, I believe at that time they said it was hyponatremia. She is currently taking gabapentin with no real affect. Her condition has not improved but has gotten various diagnosis from Fribromyalia to Issacs Syndrome.
Can you shed some light on this?
Thanks!
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